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Yale HIV/AIDS Program

General Overview

The Yale HIV/AIDS Program, formally established in 1991, is comprised of faculty, multi-disciplinary staff, and trainees who focus on HIV-related clinical care delivery, including HIV treatment and prevention; basic, translational, implementation science and clinical research occurring domestically and at international sites; clinical trials on relevant novel therapeutics and vaccines; educational programs for diverse learners in inpatient, outpatient, and community-based settings.

The mission of the Yale HIV/AIDS Program is:

  • To offer high-quality quality, competent, comprehensive, compassionate, coordinated, and culturally appropriate care to people with or at risk for HIV
  • To advance understanding of the disease pathogenesis, complications, treatment, and prevention
  • To study and/or address critical issues affecting persons with HIV such as aging, comorbid conditions such as substance use, and mental health disorders.

Program Objectives

  1. Provide expert consultation and state-of-the-art clinical services to people at risk for or living with HIV in hospital, clinic, and community settings.
  2. Foster collaborative care and research across various departments and schools within and outside Yale University to create innovative and implementable models of care to improve the lives of persons and communities affected by HIV and associated conditions.
  3. Support and develop educational and training programs to mentor and nurture the next generation of HIV providers, researchers, and patient advocates.

Clinical Services

HIV Outpatient Clinics

Yale’s outpatient clinics (formerly Nathan Smith Clinic and Haelen ID Center) are housed within the Yale New Haven Health‘s Yale Center for Infectious Diseases. The HIV outpatient service provides ambulatory care services to over 1500 gender, racially, and ethnically diverse persons with HIV.

The multidisciplinary care team includes physicians of various specialties (psychiatry, neurology, general medicine, addiction medicine, transplant), registered nurses, social workers, case managers, counselors, peer navigators, and other support staff. The outpatient clinic also provides pre-exposure prophylaxis (PrEP) services for patients at risk for HIV infection.

HIV Inpatient Care

The Donaldson Inpatient Firm of Yale New Haven Hospital, located on the 9/5 wing of the East Pavilion, is a dedicated inpatient ward staffed by Yale house staff and other trainees, and supervised by infectious diseases faculty. Together with nursing and other support staff, the firm specializes in providing clinical services for inpatient persons with HIV with HIV-related and non-HIV related complications.

Community Care Services

The Community Healthcare Van is supported by various community-based funds and provides mobile services throughout New Haven, including syringe services, pre-exposure prophylaxis (PrEP), and directly observed HIV and methadone treatment.

Meet the Clinical Teams

Yale Center for Infectious Diseases

  • HIV/AIDS

    • Professor of Medicine (Infectious Diseases) and of Epidemiology (Microbial Diseases); Affiliated Faculty, Yale Institute for Global Health; Director, Yale Center for Clinical and Community Research, Department of Medicine; Director, HIV in Prisons Program, Infectious Diseases; Director, Community Health Care Van, Intersection of Infectious Diseases and Substance Use Disorders/Addiction Medicine; Academic Icon Professor of Medicine, University of Malaya-Centre of Excellence for Research in AIDS (CERiA), Faculty of Medicine , University of Malaya

    • Associate Professor of Medicine (Infectious Diseases); Director, Yale Center for Infectious Diseases, Infectious Diseases; Program Director, HIV Primary Care Training Track, Internal Medicine; Project Director, Connecticut New England AIDS Education & Training Center, HRSA

    • Professor; Associate DIO; GME Director, Educator Development, Department of Medicine; Associate, Teaching and Learning Center; Associate Chair for Education and Academic Affairs, Internal Medicine; Director of YMS Coaching Program , Office of Curriculum

    • Associate Professor of Medicine (Infectious Diseases); Director, Cancer-ID Clinic, Internal Medicine; co-Leader, Cancer Microbiology Working Group, Yale Cancer Center

    • Assistant Professor of Medicine (Infectious Diseases; Medical Director, Information Technology-Physician Training, Yale New Haven Health System; Medical Information Officer, Information Technology, Yale New Haven Health System

    • Associate Professor of Medicine (Infectious Diseases, AIDS) and Epidemiology in the Department of Chronic Disease Epidemiology; Associate Program Director of Research, Infectious Diseases

    • Associate Professor of Medicine (Infectious Diseases); Core Faculty, Connecticut AIDS Education & Training Center; Associate Director, Office of Global Health, Yale Medicine; Co-Director, Global Health & Equity Distinction Pathway, Medicine; South Africa Site Director, Global Health Scholars Program, Yale Medicine; Affiliated Faculty, Center for Interdisciplinary Research on AIDS, Yale School of Public Health; Affiliated Faculty, Center for Methods in Implementation and Prevention Science, Yale School of Public Health; Affiliated Faculty, Yale Institute for Global Health; Co-Lead, Medicine; Associate Professor on Term, Epidemiology of Microbial Diseases

    • Professor of Medicine (AIDS) and Associate Clinical Professor of Nursing; Director, Infectious Disease Outpatient Clinic, Veterans Administration Healthcare Services, Newington

    • Gilbert H. Glaser Professor of Neurology; Division Chief, Neurological Infections & Global Neurology; Co-Director, Yale Center for Brain & Mind Health; Affiliated Faculty, Yale Institute for Global Health

    • Associate Professor Term; Director, HIV Clinical Services, Internal Medicine; Associate Professor of Clinical Internal Medicine, Yale Medicine; Program Director, Medicine, HIV Care and Prevention Program, Yale-New Haven Hospital

  • Community Health Care Van

    • Professor of Medicine (Infectious Diseases) and of Epidemiology (Microbial Diseases); Affiliated Faculty, Yale Institute for Global Health; Director, Yale Center for Clinical and Community Research, Department of Medicine; Director, HIV in Prisons Program, Infectious Diseases; Director, Community Health Care Van, Intersection of Infectious Diseases and Substance Use Disorders/Addiction Medicine; Academic Icon Professor of Medicine, University of Malaya-Centre of Excellence for Research in AIDS (CERiA), Faculty of Medicine , University of Malaya

Educational Programs

Established in 2012 within the Yale Primary Care Internal Medicine Residency Program, this three-year track trains primary care residents to become future physicians in HIV medicine. Trainees learn to provide state-of-the-art longitudinal primary care to patients with or at risk for HIV infection.

Donaldson Inpatient Rotation

This educational opportunity is one of the specialty inpatient rotations of the Internal Medicine Traditional Residency. This rotation for house staff and YSM medical students focuses on diagnostic and management approaches to the care of persons with HIV infection, encompassing additional health issues such as mental health, substance use disorders, and hepatitis C.

AIDS Education Training Center

Yale School of Medicine hosts the Connecticut site of the New England AIDS Education Training Center (AETC). The AETC was established in 1988 and is supported by Ryan White funding from the Health Resources and Services Administration. Yale HIV/AIDS Program faculty run the program which provides timely educational programs relevant to HIV care for a wide range of practitioners across Connecticut.

Faculty and Staff

  • HIV Training Track Leadership

    • Associate Professor of Medicine (Infectious Diseases); Director, Yale Center for Infectious Diseases, Infectious Diseases; Program Director, HIV Primary Care Training Track, Internal Medicine; Project Director, Connecticut New England AIDS Education & Training Center, HRSA

    • Professor; Associate DIO; GME Director, Educator Development, Department of Medicine; Associate, Teaching and Learning Center; Associate Chair for Education and Academic Affairs, Internal Medicine; Director of YMS Coaching Program , Office of Curriculum

    • Professor of Medicine (General Medicine); Director of Student Assessment, Teaching and Learning Center; Director of clinical skills assessment, Office of Education

  • Donaldson Inpatient Rotation

Research

The Yale HIV/AIDS Program boasts many well-renowned faculty of varied interests and specialties who have extensive grant-funded projects that focus on community collaborations, public health interfaces with HIV/AIDS, and service delivery models for associated conditions. Some areas of focus are highlighted below:

International

  • Implementation science to scale up HIV prevention and treatment in Eastern Europe/Central Asia
  • Innovations to promote HIV testing and PrEP in men who have sex with men and transgender women
  • Trials of long-acting injectables for HIV prevention and opiate use disorder
  • Integration of HIV and tuberculosis care

Domestic

  • Integrating substance use treatment research with infectious diseases
  • Providing access to medication-assisted treatment for opiate use disorder to persons in prison and jail
  • Providing services focused on HIV and women’s health
  • Providing community collaborative models to improve care for persons with HIV and hepatitis C, and aging in persons with HIV

Antivirals and Vaccines Clinical Trials

  • Antivirals and vaccines research through the Yale Antivirals and Vaccine Research Program which studies novel therapeutics and strategies for HIV treatment and prevention; and vaccines for multiple infectious diseases including bacterial and viral infections (e.g. SARS-CoV-2).

HIV/AIDS Care at Yale

Yale doctors have been caring for patients with HIV and AIDS since the first U.S. cases of what was at the time an unknown and deadly illness were reported in 1981. Over the last four decades, medical advances have transformed HIV into a chronic disease, which, if treated, barely shortens life expectancy.

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Specific HIV/AIDS Program Focus Areas

  • Yale Ryan White Program

    Supports the care of persons with HIV, functioning as a safety net for persons who are under-resourced for care in New Haven County.

  • Yale HIV and Aging Program

  • Antivirals and Vaccines Research Program

  • Implementation Science (Eastern Europe/Central Asia)

    Scale up HIV prevention and treatment in eastern Europe and central Asia.

  • Infectious Diseases & Substance Use Disorders

    Investigating the interface of infectious diseases and substance use disorders using implementation science strategies for integrating addiction and HIV treatment into primary care settings.

  • mHealth & Telehealth for HIV Prevention

    Researchers within infectious diseases are creating and implementing strategies using mHealth or telehealth to prevent HIV in men who have sex with men and transgender women.

  • Yale Clinical & Community Research

    Research at the interface of infectious diseases, substance abuse, and the criminal justice system.

  • Center for Implementation Science Malaysian Implementation Science Training (MIST) Program

  • InSTRIDE and InMOTION

  • Yale HIV Neuro Group

    Studying the mechanisms underlying damage to the central nervous system in HIV and other infections.

  • Women’s Health & HIV

    Yale’s women’s health and HIV research addresses the social and structural factors that impact a woman’s HIV risk.

  • HIV & Cancer

    Research efforts include studies on understanding social determinants of health and cancer care inequities to improve outcomes as well as basic science collaborations to better understand pathophysiology.

  • HIV & Tuberculosis

    This research group conducts clinical research that aims to improve tuberculosis and HIV outcomes in resource-limited settings.