2022
Response of Human Toll–Like Receptor 2 During the Infection of Leptospirosis
Kappagoda C, Senavirathna I, Warnasekara J, Srimantha S, De Silva N, Agampodi S. Response of Human Toll–Like Receptor 2 During the Infection of Leptospirosis. International Journal Of Infectious Diseases 2022, 116: s71. DOI: 10.1016/j.ijid.2021.12.167.Peer-Reviewed Original ResearchToll-like receptor2Human TLR2 geneTLR2 geneMouse modelToll-like receptor 2Human Toll-like receptor 2Results 64 patientsInnate immune responsePathogenic Leptospira sppGene expression analysisImmune responseStudy populationReceptor 2Receptor responsesTLR2 regulationPatientsLeptospirosisLeptospira sppNew therapeuticsWhole bloodGene expression studiesGene amplificationReverse transcriptaseInfectionTotal RNA
2019
A Case–Control Study of Environmental and Occupational Risks of Leptospirosis in Sri Lanka
Schønning MH, Phelps MD, Warnasekara J, Agampodi SB, Furu P. A Case–Control Study of Environmental and Occupational Risks of Leptospirosis in Sri Lanka. EcoHealth 2019, 16: 534-543. PMID: 31664587, DOI: 10.1007/s10393-019-01448-w.Peer-Reviewed Original ResearchConceptsPaddy workersOdds ratioSignificant higher riskCase-control studyHigher odds ratioPublic health interventionsTransmission of leptospirosisRisk factorsOccupational exposureProtective effectHigh riskHigh incidenceRat exposureHuman leptospirosisViral infectionHealth interventionsZoonotic infectionOccupational riskLeptospirosisLeptospirosis transmissionStudy sampleOccupational groupsInfectionStructured interviewsHousehold animals
2014
Hantavirus infection mimicking leptospirosis: how long are we going to rely on clinical suspicion?
Dahanayaka NJ, Agampodi SB, Bandaranayaka AK, Priyankara S, Vinetz JM. Hantavirus infection mimicking leptospirosis: how long are we going to rely on clinical suspicion? The Journal Of Infection In Developing Countries 2014, 8: 1072-5. PMID: 25116678, DOI: 10.3855/jidc.4115.Peer-Reviewed Original ResearchConceptsHantavirus infectionPopulation-based prospective studyDiagnostic facilitiesAcute hantavirus infectionClassical clinical pictureCases of leptospirosisClinical suspicionClinical pictureProspective studyEpidemiological featuresRetrospective analysisInfectious diseasesInfectionSerum samplesMedical staffLeptospirosisLeptospirosis outbreaksFeverDiseaseDiagnosisSuspicionSri Lanka
2013
Massive hepatitis A outbreak in Sri Lanka in 2009: an indication of increasing susceptibility and epidemiological shift?
Dahanayaka N, Kiyohara T, Agampodi S. Massive hepatitis A outbreak in Sri Lanka in 2009: an indication of increasing susceptibility and epidemiological shift? Sri Lankan Journal Of Infectious Diseases 2013, 3: 28. DOI: 10.4038/sljid.v3i2.5640.Peer-Reviewed Original Research
2010
Incidence and effects of Varicella Zoster Virus infection on academic activities of medical undergraduates - a five-year follow-up study from Sri Lanka
Agampodi SB, Dharmaratne SD, Thevanesam V, Dassanayake S, Kumarihamy P, Ratnayake A. Incidence and effects of Varicella Zoster Virus infection on academic activities of medical undergraduates - a five-year follow-up study from Sri Lanka. BMC Infectious Diseases 2010, 10: 117. PMID: 20465846, PMCID: PMC2882915, DOI: 10.1186/1471-2334-10-117.Peer-Reviewed Original ResearchConceptsVaricella-zoster virus infectionZoster virus infectionVZV infectionPerson yearsVirus infectionFive-year followNumber of infectionsSelf-administered structured questionnaireVZV immunizationConclusionsThe incidenceCumulative incidenceRetrospective cohortIncidence densityMedical undergraduatesStudy cohortIncidence rateClinical appointmentsAdult populationInfectionSusceptible cohortCohortIncidenceUniversity of PeradeniyaSecond questionnaireSri Lankan medical undergraduates
2009
Susceptibility of New Entrant University Students in Sri Lanka to Varicella Zoster Infection
Kurukulasooriya GM, Thevanesam V, Agampodi SB, Abeykoon AM, Amarasiri SP, Goonasekera KP. Susceptibility of New Entrant University Students in Sri Lanka to Varicella Zoster Infection. Asia Pacific Journal Of Public Health 2009, 22: 219-224. PMID: 19411280, DOI: 10.1177/1010539509334625.Peer-Reviewed Original ResearchConceptsVZV IgG antibodiesChicken poxIgG antibodiesVaricella-zoster virus infectionCross-sectional descriptive studyVaricella zoster infectionZoster virus infectionHistory of infectionSelf-reported historyZoster infectionMedian ageVZV infectionSeropositive rateSerological evaluationVirus infectionStudy populationNegative historyInfectionDescriptive studyInterquartile rangeUniversity of PeradeniyaAgeAntibodiesPresent studyYears