2024
The respiratory syncytial virus vaccines are here: Implications for solid organ transplantation
Trubin P, Azar M, Kotton C. The respiratory syncytial virus vaccines are here: Implications for solid organ transplantation. American Journal Of Transplantation 2024, 24: 897-904. PMID: 38341028, DOI: 10.1016/j.ajt.2024.02.003.Peer-Reviewed Original ResearchRespiratory syncytial virusSolid organ transplantationLower respiratory tract diseaseHigh risk of infectious complicationsBurden of RSV diseaseOrgan transplantationRisk of infectious complicationsRespiratory syncytial virus vaccineRespiratory tract diseaseCenters for Disease Control and Prevention's Advisory CommitteeOrgan transplant recipientsSolid organ recipientsPoor clinical outcomesFood and Drug AdministrationRSV F glycoproteinRespiratory virus vaccinesRSV diseaseInfectious complicationsTransplant recipientsClinical outcomesSyncytial virusClinical decision-makingImmunocompromised individualsOrgan recipientsImmunization Practices
2023
Rapid antimicrobial resistance detection methods for bloodstream infection in solid organ transplantation: Proposed clinical guidance, unmet needs, and future directions
Turbett S, Banach D, Bard J, Gandhi R, Letourneau A, Azar M. Rapid antimicrobial resistance detection methods for bloodstream infection in solid organ transplantation: Proposed clinical guidance, unmet needs, and future directions. Transplant Infectious Disease 2023, 25: e14113. PMID: 37594214, DOI: 10.1111/tid.14113.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsUnmet needSolid organ transplant recipientsOrgan transplant recipientsSolid organ transplantationTransplant infectious diseasesEffective antimicrobial therapyPositive blood culturesFast institutionSOT recipientsTransplant recipientsDiagnostic stewardshipBloodstream infectionsAntimicrobial therapyBlood culturesClinical guidanceOrgan transplantationConsensus conferenceClinical practiceInfectious diseasesClinical microbiologyAmerican SocietyTransplantationResistance detectionBacterial resistanceRecipientsCurrent Concepts in the Diagnosis and Management of Pneumocystis Pneumonia in Solid Organ Transplantation
Trubin P, Azar M. Current Concepts in the Diagnosis and Management of Pneumocystis Pneumonia in Solid Organ Transplantation. Infectious Disease Clinics Of North America 2023, 37: 617-640. PMID: 37142510, DOI: 10.1016/j.idc.2023.03.005.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsSolid organ transplant recipientsOrgan transplant recipientsFirst-choice agentsSolid organ transplantationAppropriate clinical contextTransplant recipientsInterstitial pneumoniaTrimethoprim-sulfamethoxazoleOptimal treatmentPneumocystis pneumoniaOrgan transplantationInfection manifestsPrevention strategiesNucleic acid amplificationDiagnostic testingRadiographic imagingTissue samplingClinical contextLung fluidCurrent conceptsHost susceptibilityPneumoniaAcid amplificationTreatmentProphylaxis
2021
Transplant Adenovirus Infection: Clinical Syndromes, Diagnosis, and Management
Malinis M, Azar M. Transplant Adenovirus Infection: Clinical Syndromes, Diagnosis, and Management. 2021, 781-805. DOI: 10.1007/978-3-030-25869-6_33.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsSolid organ transplant recipientsInadequate clinical responseReduction of immunosuppressionCornerstone of treatmentOrgan transplant recipientsSolid organ transplantationManifestations of diseaseDirect antigen detectionGraft dysfunctionGraft lossImmunosuppression reductionTransplant recipientsClinical responseAntiviral therapySignificant morbidityAsymptomatic sheddingTherapeutic optionsViral cultureClinical syndromeAdenoviral diseaseOrgan transplantationHematopoietic stem cellsAntigen detectionAdenovirus infectionInfection
2020
Diagnostic Testing of COVID-19 in Solid Organ Transplantation: Current Clinical Application and Future Strategies
Trubin PA, Azar MM, Malinis M. Diagnostic Testing of COVID-19 in Solid Organ Transplantation: Current Clinical Application and Future Strategies. Current Transplantation Reports 2020, 7: 390-398. PMID: 33134033, PMCID: PMC7585558, DOI: 10.1007/s40472-020-00307-w.Peer-Reviewed Original ResearchSARS-CoV-2 infectionSolid organ transplantationInfection prevention practicesOrgan transplantationTransplant recipientsPolymerase chain reactionAcute respiratory syndrome coronavirus 2 infectionSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infectionSolid organ transplant recipientsSyndrome coronavirus 2 infectionPrevention practicesCOVID-19 pandemicRecipient suitabilityCoronavirus 2 infectionOrgan transplant recipientsChain reactionCoronavirus disease 2019SARS-CoV-2Current clinical applicationsDiagnostic testing strategiesCOVID-19 diagnosticsMitigation of infectionPurpose of ReviewWhileOptimal donorViral kineticsTransplant Adenovirus Infection: Clinical Syndromes, Diagnosis, and Management
Malinis M, Azar M. Transplant Adenovirus Infection: Clinical Syndromes, Diagnosis, and Management. 2020, 1-25. DOI: 10.1007/978-3-030-01751-4_33-1.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsSolid organ transplant recipientsInadequate clinical responseReduction of immunosuppressionCornerstone of treatmentOrgan transplant recipientsSolid organ transplantationManifestations of diseaseDirect antigen detectionGraft dysfunctionGraft lossImmunosuppression reductionTransplant recipientsClinical responseAntiviral therapySignificant morbidityAsymptomatic sheddingTherapeutic optionsViral cultureClinical syndromeAdenoviral diseaseOrgan transplantationHematopoietic stem cellsAntigen detectionAdenovirus infectionInfection