2016
Sensitive Detection and Simultaneous Discrimination of Influenza A and B Viruses in Nasopharyngeal Swabs in a Single Assay Using Next-Generation Sequencing-Based Diagnostics
Zhao J, Liu J, Vemula SV, Lin C, Tan J, Ragupathy V, Wang X, Mbondji-wonje C, Ye Z, Landry ML, Hewlett I. Sensitive Detection and Simultaneous Discrimination of Influenza A and B Viruses in Nasopharyngeal Swabs in a Single Assay Using Next-Generation Sequencing-Based Diagnostics. PLOS ONE 2016, 11: e0163175. PMID: 27658193, PMCID: PMC5033603, DOI: 10.1371/journal.pone.0163175.Peer-Reviewed Original ResearchB virusInfluenza AInfluenza types/subtypesInfluenza virusPandemic influenza virusInfluenza B virusTypes/subtypesInfluenza viral genomeE627K mutationAntiviral treatmentNasopharyngeal swabsInfluenza strainsLaboratory confirmationPandemic potentialS31N mutationPatient specimensClinical settingNGS assaysDrug resistance markersVirusFurther studiesCurrent diagnostic platformsPublic healthK mutationInfluenzaImmunoglobulin M for Acute Infection: True or False?
Landry ML. Immunoglobulin M for Acute Infection: True or False? MSphere 2016, 23: 540-545. PMID: 27193039, PMCID: PMC4933779, DOI: 10.1128/cvi.00211-16.Peer-Reviewed Original ResearchConceptsClear clinical utilityFalse-positive IgMImmunoglobulin M testAcute infectionInappropriate therapyFalse-positive resultsDiagnostic workupEpidemiologic findingsIgM detectionInfection controlClinical utilityImmunoglobulin MSerial samplesAccurate diagnosisPremature closurePublic healthTherapyNumerous reportsDiagnosisPatientsPrognosisIgMWorkupInfectionClinicians
2008
An Outbreak of Concurrent Echovirus 30 and Coxsackievirus A1 Infections Associated with Sea Swimming among a Group of Travelers to Mexico
Begier EM, Oberste MS, Landry ML, Brennan T, Mlynarski D, Mshar PA, Frenette K, Rabatsky-Ehr T, Purviance K, Nepaul A, Nix WA, Pallansch MA, Ferguson D, Cartter ML, Hadler JL. An Outbreak of Concurrent Echovirus 30 and Coxsackievirus A1 Infections Associated with Sea Swimming among a Group of Travelers to Mexico. Clinical Infectious Diseases 2008, 47: 616-623. PMID: 18637756, DOI: 10.1086/590562.Peer-Reviewed Original ResearchConceptsEchovirus 30Enteroviral infectionNucleic acid amplification testingIllness onset datesUninfected control subjectsPoint-source exposureMultiple enterovirusesAseptic meningitisFrequent symptomsIllness onsetViral cultureAmplification testingControl subjectsCerebrospinal fluidHuman stoolInfectionNauseaConnecticut DepartmentStoolCoxsackievirus (CV) A1Public healthIllnessEnterovirusesMolecular amplificationGroups of travelers