1985
The Treatment of Pneumocystis carinii Pneumonia in the Acquired Immunodeficiency Syndrome
Small C, Harris C, Friedland G, Klein R. The Treatment of Pneumocystis carinii Pneumonia in the Acquired Immunodeficiency Syndrome. JAMA Internal Medicine 1985, 145: 837-840. PMID: 3873229, DOI: 10.1001/archinte.1985.00360050081015.Peer-Reviewed Original ResearchConceptsPneumocystis carinii pneumoniaImmunodeficiency syndromeAdverse reactionsCarinii pneumoniaEpisodes of PCPRecurrent Pneumocystis carinii pneumoniaAcquired Immunodeficiency SyndromeUnresponsive infectionsLate recurrenceTrimethoprim-sulfamethoxazolePatientsAdditional episodesSyndromeTherapySecond weekPneumoniaEpisodesImmediate reactionsFailure rateLeukopeniaRashFeverRecurrenceHepatotoxicityInfection
1983
Community-acquired opportunistic infections and defective cellular immunity in heterosexual drug abusers and homosexual men
Small C, Klein R, Friedland G, Moll B, Emeson E, Spigland I. Community-acquired opportunistic infections and defective cellular immunity in heterosexual drug abusers and homosexual men. The American Journal Of Medicine 1983, 74: 433-441. PMID: 6219579, DOI: 10.1016/0002-9343(83)90970-1.Peer-Reviewed Original ResearchConceptsOpportunistic infectionsSevere opportunistic infectionsHomosexual menDrug abusersOral thrushCellular immunityT helper/inducer cellsT suppressor/cytotoxic cellsHelper/inducer cellsSuppressor/cytotoxic cellsHealthy young patientsSyndrome of immunodeficiencyPneumocystis carinii pneumoniaMycobacterium intracellulare infectionDefective cellular immunityWhite homosexual menCutaneous anergyCandida esophagitisYounger patientsNonspecific findingsClinical presentationCarinii pneumoniaCytotoxic cellsInducer cellsIntracellulare infection
1982
Inverted ratio of inducer to suppressor T-lymphocyte subsets in drug abusers with opportunistic infections
Moll B, Emeson E, Small C, Friedland G, Klein R, Spigland I. Inverted ratio of inducer to suppressor T-lymphocyte subsets in drug abusers with opportunistic infections. Clinical Immunology 1982, 25: 417-423. PMID: 6218947, DOI: 10.1016/0090-1229(82)90206-9.Peer-Reviewed Original ResearchConceptsT lymphocyte subsetsOpportunistic infectionsOnly opportunistic infectionPercentage of T8Pneumocystis carinii pneumoniaPercentage of T4Ratio of inducerCutaneous anergyCarinii pneumoniaImmune statusPeripheral bloodOral candidiasisProliferative responsePatientsDrug abusersDrug abuseMarked reductionInfectionP. cariniiLymphocytesFurther evidencePneumoniaAnergyHistoplasmosisCandidiasis