What is it Like to Live with Brain Fog?
Akiko Iwasaki, Yale professor of immunobiology and WHRY collaborator, is the co-author of a review article on Covid-19 related cognitive impairment. The condition has affected people with cancer and other chronic conditions for years, but long Covid is just beginning to push it into the spotlight.Source: Washington Post
Apply Now For DRC Project Grants
Applications are being accepted for pilot and feasibility project grants from the Yale Diabetes Research Center (DRC). The grants will provide seed money for investigators to explore the feasibility of diabetes or metabolism-related studies and to obtain sufficient data to further pursue such lines of investigation via other funding mechanisms.
Will Long COVID Research Provide Answers for Poorly Understood Diseases Like ME/CFS?
ME/CFS (myalgic encephalomyelitis/chronic fatigue syndrome) is a highly disabling, severe condition that has been largely overlooked and even questioned as an illness by physicians and biomedical researchers for decades. But now, scientists including Yale's Akiko Iwasaki and Harlan Krumholz are finding parallels between post-infection long COVID and ME/CFS.
COVID-19 Virus Increases Risk for Other Infections by Disrupting Normal Mix of Gut Bacteria
Infection with the pandemic virus, SARS-CoV-2, can reduce the number of bacterial species in a patient’s gut, with the lesser diversity creating space for dangerous microbes to thrive, a new study finds.Source: NYU Langone Health
Researchers Probe Why Vaccine Responses Differ From Person to Person
A team of researchers led by Yale School of Medicine’s Steven Kleinstein, PhD, is striving to understand why some people’s immune systems generate a robust protective response post-vaccination while others’ fail, and how this differs across vaccines. The team has published a series of new papers on its investigations.
‘Prime and Spike’ Nasal Vaccine Strategy Helps Combat COVID
The new “prime” and “spike” approach may help prevent breakthrough infections of vaccinated individuals by bolstering immune response within the mucosal lining of the respiratory tract, which are the first cells attacked by COVID-19.Source: YaleNews
New Findings on Endometrial Cancer Treated With Pembrolizumab
New research from Yale Cancer Center reveals for the first time ever a differential clinical response to pembrolizumab in Lynch-like (mutated) vs methylated microsatellite instability-high (MSI-H) uterine cancer patients, increasing our understanding about the proportion of patients that derive benefit from immune checkpoint blockade.
Yale Researchers Awarded $12M NIH Grant to Study Impact of FGF21 Protein on Aging
Researchers from Yale University, and the University of Texas Southwestern Medical Center have been awarded a $12.4 million, five-year grant from the National Institute on Aging of the NIH to deploy their unique research models and expertise in a coordinated fashion to develop a novel course of gerontological research.
New Mouse Model Provides Unprecedented Look at Human Immune System
Despite the critical role of neutrophils in the human immune system, no one has been able to study them in a living context, limiting investigations of their properties. But now, a team of Yale researchers has developed the first humanized mouse model that will permit research on neutrophils in vivo.
Schatz to Receive Paul Ehrlich and Ludwig Darmstaedter Prize
Immunologists David G. Schatz of Yale School of Medicine and Frederick W. Alt of Harvard Medical School are to receive the 2023 Paul Ehrlich and Ludwig Darmstaedter Prize. The two researchers are being acknowledged for their discovery of molecules and mechanisms that enable our immune system to perform the astounding feat of recognizing billions of different antigens on first contact.Source: YaleNews