Richard Flavell, PhD, FRS

Sterling Professor of Immunobiology; Investigator, Howard Hughes Medical Institute

Departments & Organizations

Immunobiology: Flavell Lab | Human and Translational Immunology Program

Center for RNA Science and Medicine

Diabetes Research Center

Fellowship Training

Liver Center

NIH T32 Program

Rheumatic Diseases Research Core

SPORE in Skin Cancer

Vascular Biology and Therapeutics Program

Yale Cancer Center: Cancer Immunology | K12 Calabresi Immuno-Oncology Training Program (IOTP)

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Computational Biology and Bioinformatics | Immunology | Microbiology

Yale Cooperative Center of Excellence in Hematology (YCCEH)

Yale Stem Cell Center

Office of Cooperative Research


Dr. Flavell is Sterling Professor of Immunobiology at Yale University School of Medicine, and an Investigator of the Howard Hughes Medical Institute. He received his B.Sc. (Honors) in 1967 and Ph.D. in 1970 in biochemistry from the University of Hull, England, and performed postdoctoral work in Amsterdam (1970-72) with Piet Borst and in Zurich (1972-73) with Charles Weissmann. Before accepting his current position in 1988, Dr. Flavell was first Assistant Professor (equivalent) at the University of Amsterdam (1974-79); then Head of the Laboratory of Gene Structure and Expression at the National Institute for Medical Research, Mill Hill, London (1979-82); and subsequently President and Chief Scientific Officer of Biogen Research Corporation, Cambridge, Massachusetts (1982-88). Dr. Flavell is a fellow of the Royal Society, a member of the National Academy of Sciences as well as the Institute of Medicine. Richard Flavell uses transgenic and gene-targeted mice to study Innate and Adaptive immunity, T cell tolerance and activation in immunity and autoimmunity,apoptosis, and regulation of T cell differentiation.

Education & Training

PhD Hull University (1970)
EMBO Postdoctoral Fellow with Prof. C. Weissmann Universitat Zurich
Postdoctoral Fellow with Professor Piet Borst University of Amsterdam

Honors & Recognition

  • The Vilcek Prize in Biomedical ScienceVilcek Foundation (2013)

  • The William B. Coley Award for Distinguished Research in Basic and Tumor ImmunologyCancer Research Institute (2012)


  • Mouse Model to Evaluate Attenuated Vaccine Candidates Switzerland (2008)

    The primary objective of this proposal is to generate a humanized mouse model in which critical components of the human immune system replace the homologous regions of the mouse.

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Contact Info

Richard Flavell, PhD, FRS
Lab Location
The Anlyan Center
300 Cedar Street, Ste S560, S570

New Haven, CT 06519
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Office Location
The Anlyan Center
300 Cedar Street, Ste Suite 569A

New Haven, CT 06519
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Mailing Address
ImmunobiologyPO Box 208011
300 Cedar Street

New Haven, CT 06520

Curriculum Vitae

Flavell Lab