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Scientists uncovered self-renewing immune cells that continually supply T cells that damage the kidneys in lupus patients.

While the research team was surprised by the results, David Hafler, MD, professor of immunobiology and former chairman of the Department of Neurology at Yale School of Medicine, New Haven, Connecticut, was not. “I wasn’t surprised, but I was really very delighted to see more evidence of the gut-brain [connection],” he said (he was not involved in the study).

The researchers joined the Immune Cell Reprogramming team, which aims to harness immune cells for health surveillance and disease treatment.

Cole Jensen, MPH, a PhD Student in Computational Biology and Bioinformatics, was recently awarded a prestigious National Institutes of Health (NIH) F31 award.

“We know that some people experience prolonged and debilitating symptoms after vaccination, and this warrants further clinical, epidemiological and mechanistic studies to better understand what causes these illnesses,” said Akiko Iwasaki, an immunologist at Yale who studies post-vaccine syndrome and its similarity to long Covid.

A Yale team has identified a type of RNA that boosts the replication of HIV, an unexpected discovery that changes how scientists understand the virus and how it may one day be stopped.

A new study explains why certain people experience worse colds than others, along with a few ways to manage symptoms. To conduct the study, researchers created a laboratory model of the lining of the human nasal passages, says Ellen F. Foxman, MD, PhD, associate professor of laboratory medicine and immunobiology at Yale School of Medicine and senior author of the article. Using this model, they examined how this community of cells in the nose responds to rhinovirus infection.

Akiko Iwasaki, a professor of immunology at Yale School of Medicine who was not involved in the study but calls it “very interesting.” “In humans, there are different structures in the nose and the throat and the deeper lung,” she says. “Whether or not this type of vaccination can induce similar structures in humans is something that needs to be tested.”

With the recent launch of HealthTech Works, Yale Ventures now has five accelerator funds focused on translating academic excellence into real-world impact.