Yale Center for Research on Aging Y-Age Symposium 2023

Tremendous scientific progress in modern medicine over the last century has helped to eliminate many former causes of premature human mortality and increase lifespan. By 2030, people aged 65 and older will outnumber individuals under the age of 18 for the first time in US history. Over the next 20-30 years, the number of people over the age of 80 throughout the world is expected to triple. However, aging remains the single biggest risk factor for diseases and despite progress, the equivalent increase in healthspan– the length of time that a person is in good health, has stalled.

In the inaugural symposium of Yale Center for Research on Aging (Y-Age), world renowned experts and panelists will address essential aspects of basic and clinical research that underlie the process of aging, disease and longevity. The speakers will cover topics related to immune dysfunction, senescence, inflammaging, cancer, neurodegeneration and dietary interventions of longevity. Panel discussion led by Drs. Ron Kohanski (NIA), Don Ingram (LSU), and Stephen Helfand (Brown University), at the end of this one-day event will identify the common themes, challenges, open questions and future directions in aging research and its impact on human health.

LEARNING OBJECTIVES

1. Understanding the causes of aging.
2. How the decline of immune system function affect aging process?
3. How the interaction of immune and metabolic systems participates in aging, health and disease?
4. What is inflammaging, its causes and consequences?
5. Experimental approaches for lifespan and healthspan extension.