Regulation of osteoblasts by alkaline phosphatase in ankylosing spondylitis
Jo S, Han J, Lee YL, Yoon S, Lee J, Wang SE, Kim T. Regulation of osteoblasts by alkaline phosphatase in ankylosing spondylitis. International Journal Of Rheumatic Diseases 2018, 22: 252-261. PMID: 30415492, DOI: 10.1111/1756-185x.13419.Peer-Reviewed Original ResearchConceptsHealthy controlsPrimary CTAS patientsAge-matched healthy controlsRheumatoid arthritis patientsAlkaline phosphatase levelsPossible therapeutic targetOsteoblast differentiationAlkaline phosphataseALP activityRunt-related transcription factor 2RA groupArthritis patientsMale patientsPrimary diseaseSpinal ankylosisRegulation of osteoblastSerum ALPPhosphatase levelsTherapeutic targetALP levelsTranscription factor 2Master transcriptional factorPatientsOsteoblastic activity