LGI1 governs neuritin-mediated resilience to chronic stress
Lee S, Kim N, Choi M, Ko S, Wang S, Jo H, Seo J, Kim Y, Kim H, Lee H, Kim J, Son H. LGI1 governs neuritin-mediated resilience to chronic stress. Neurobiology Of Stress 2021, 15: 100373. PMID: 34401409, PMCID: PMC8350063, DOI: 10.1016/j.ynstr.2021.100373.Peer-Reviewed Original ResearchLeucine-rich glioma-inactivated protein 1Chronic unpredictable stressLGI1 expressionAntidepressant-like behaviorHippocampus of miceHistone deacetylase 5 (HDAC5) phosphorylationDevelopment of CNSInsulin receptor inhibitorNeuronal atrophyFlox/Unpredictable stressReceptor inhibitorsChronic stressNeuritinHDAC5 phosphorylationProtein 1Pathological depressionMetastasis suppressorEndogenous proteinsNeurite outgrowthMiceDepressionStress resilienceCritical roleExpression