Rab GTPases and Membrane Trafficking in Neurodegeneration
Kiral F, Kohrs F, Jin E, Hiesinger P. Rab GTPases and Membrane Trafficking in Neurodegeneration. Current Biology 2018, 28: r471-r486. PMID: 29689231, PMCID: PMC5965285, DOI: 10.1016/j.cub.2018.02.010.Peer-Reviewed Original ResearchConceptsMembrane traffickingRab GTPasesCellular responsesRab GTPase functionGTPase functionMembrane compartmentsGTPasesKey regulatorSecondary consequenceHallmark of neurodegenerationTraffickingSecondary correlateDrivers of pathologyCurrent knowledgeNeurodegenerationHuntington's diseaseMembraneDifferent rolesRegulatorAlzheimer's diseaseCompartmentsDefectsHallmarkDirect consequenceFunction