2019
In vivo analysis of renal epithelial cells in zebrafish
Li Y, Xu W, Jerman S, Sun Z. In vivo analysis of renal epithelial cells in zebrafish. Methods In Cell Biology 2019, 154: 163-181. PMID: 31493817, DOI: 10.1016/bs.mcb.2019.04.016.Peer-Reviewed Original Research
2017
Axonemal dynein assembly requires the R2TP complex component Pontin
Li Y, Zhao L, Yuan S, Zhang J, Sun Z. Axonemal dynein assembly requires the R2TP complex component Pontin. Development 2017, 144: 4684-4693. PMID: 29113992, PMCID: PMC5769618, DOI: 10.1242/dev.152314.Peer-Reviewed Original ResearchConceptsDynein arm assemblyCilia motilityTah1-Pih1 (R2TP) complexAxonemal dynein assemblyMacromolecular protein complexesIntermediate chain 1Reptin functionsRUVBL1-RUVBL2R2TP complexAAA ATPasesCytosolic punctaArm assemblyDynein assemblyAssembly factorsCytosolic fociProtein complexesZebrafish embryosCilia defectsInner dynein armsPontinCiliated tissuesMouse testisReptinChain 1Dynein arms
2013
Reptin/Ruvbl2 is a Lrrc6/Seahorse interactor essential for cilia motility
Zhao L, Yuan S, Cao Y, Kallakuri S, Li Y, Kishimoto N, DiBella L, Sun Z. Reptin/Ruvbl2 is a Lrrc6/Seahorse interactor essential for cilia motility. Proceedings Of The National Academy Of Sciences Of The United States Of America 2013, 110: 12697-12702. PMID: 23858445, PMCID: PMC3732945, DOI: 10.1073/pnas.1300968110.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAxonemal DyneinsAxonemeCiliaDNA DamageMutationNuclear ProteinsZebrafishZebrafish ProteinsConceptsDNA damage responseCilia motilityDamage responseAxonemal dynein armsReptin functionsDefective cilia motilityVertebrate developmentTranscriptional regulationVivo functionCiliary defectsMutantsPCD genesReptinRUVBL2Expression levelsZebrafishSeahorsesDynein armsAutosomal recessive diseasePrimary ciliary dyskinesiaMotilityMultiple processesArm formationRecessive diseaseInteractors
2011
Lzts2 Regulates Embryonic Cell Movements and Dorsoventral Patterning through Interaction with and Export of Nuclear β-Catenin in Zebrafish*
Li Y, Li Q, Long Y, Cui Z. Lzts2 Regulates Embryonic Cell Movements and Dorsoventral Patterning through Interaction with and Export of Nuclear β-Catenin in Zebrafish*. Journal Of Biological Chemistry 2011, 286: 45116-45130. PMID: 22057270, PMCID: PMC3248021, DOI: 10.1074/jbc.m111.267328.Peer-Reviewed Original ResearchConceptsCE movementsDorsoventral patterningMidline convergenceΒ-cateninNuclear β-cateninEmbryonic cell movementsWnt/β-catenin activityActivation of BMPΒ-catenin activityOrgan precursorsVertebrate embryogenesisActivation of STAT3Zygotic expressionBMP signalingRedundant functionsMidline progenitorsZebrafish embryosEarly embryosCell movementOrgan progenitorsEctopic expressionEmbryonic cellsVentralized embryosCanonical WntLZTS2