Caveolin-1 regulates dorsoventral patterning through direct interaction with β-catenin in zebrafish
Mo S, Wang L, Li Q, Li J, Li Y, Thannickal V, Cui Z. Caveolin-1 regulates dorsoventral patterning through direct interaction with β-catenin in zebrafish. Developmental Biology 2010, 344: 210-223. PMID: 20452340, DOI: 10.1016/j.ydbio.2010.04.033.Peer-Reviewed Original ResearchConceptsZebrafish embryogenesisDorsoventral patterningCav-1Caveolin-1Dorsal organizer formationPlasma membrane caveolaeWnt/beta-catenin pathwayEarly vertebrate embryosNuclear translocationBeta-catenin pathwayCav-1 functionCav-1 proteinVentralizing activityVertebrate embryosBMP signalsDorsal genesOrganizer formationMembrane caveolaeCav-1 knockdownEmbryonic developmentEctopic expressionTranscriptional expressionCanonical WntDorsal activityΒ-catenin