Woo Sub Yang
Associate Research Scientist in GeneticsAbout
Research
Publications
2026
Bidens pilosa extract and bentonite, a phytogenic formulation, as a feed additive to improve diarrhea and gut microbiota in calves: Effects on feed use and regulation of gut microbiota
Lee Y, Kuo T, Yang G, Liang Y, Yang W. Bidens pilosa extract and bentonite, a phytogenic formulation, as a feed additive to improve diarrhea and gut microbiota in calves: Effects on feed use and regulation of gut microbiota. Veterinary And Animal Science 2026, 34: 100732. DOI: 10.1016/j.vas.2026.100732.Peer-Reviewed Original ResearchGut microbiotaBacterial generaRegulation of gut microbiotaFeces of calvesCulture-based methodsHolstein-Friesian calvesRRNA sequencingMetagenomic analysisIntestine of calvesGrowth of bacteriaBody weight gainPathogenic potentialMicrobiotaBacterial growthFecal IgA levelsBidens pilosa extractFecal scoreFriesian calvesGrowth performanceFeed useGutFeed additivesGenusLivestock industryAnimal healthRegulation of Nosema ceranae gene expression by Bidens pilosa phytogenic treatment in infected honey bees
Li Y, Chen K, Chang J, Chang Z, Ko C, Ho S, Chen L, Wu M, Yang W, Yang Y, Chen Y, Nai Y. Regulation of Nosema ceranae gene expression by Bidens pilosa phytogenic treatment in infected honey bees. Frontiers In Insect Science 2026, 6: 1828903. PMID: 42318229, PMCID: PMC13273367, DOI: 10.3389/finsc.2026.1828903.Peer-Reviewed Original ResearchBee midgutV-type ATPaseHoney beesPathogen loadHoney bee midgutTranscriptome profilingDays post-infectionMolecular basisGene expressionInfected honey beesLaboratory cage experimentsEarly infection stageRNAi-mediated knockdownPhytogenic extractsWorker beesMicrosporidian parasitePost-infectionStage-dependent mannerInfection stagesCage experimentsGene OntologyRNAi resultsTranscriptome analysisBeesParasite genesA New Vista of Opportunity in Diabetes Management: Natural Product‐Based β‐cell Preservation
Lee Y, Kuo T, Yang C, Yang G, Yang W. A New Vista of Opportunity in Diabetes Management: Natural Product‐Based β‐cell Preservation. Food Chemistry International 2026 DOI: 10.1002/fci2.70065.Peer-Reviewed Original ResearchPositive regulatorResistance to cell deathNegative regulatorInsulin synthesis/secretionB cell homeostasisB cellsCell deathNatural compoundsOphiocordyceps sinensisRegulation of B cellsMolecular mechanismsDisease developmentStructural classesB-cell massPeganum harmalaInsulin secretionMolecular targetsNatural inhibitorFunctional B cellsTarget identificationNatural productsBidens pilosaDatabase searchCurcuma longaPatient‐Specific Computational Flow Simulation Reveals Adverse Hemodynamic Factors Associated With Occlusion of Directional Branches After Fenestrated‐Branched Endovascular Aneurysm Repair
Tran K, Chait J, Tenorio E, Yang W, Marsden A, Mendes B, Lee J, Oderich G. Patient‐Specific Computational Flow Simulation Reveals Adverse Hemodynamic Factors Associated With Occlusion of Directional Branches After Fenestrated‐Branched Endovascular Aneurysm Repair. Journal Of The American Heart Association 2026, 15: e044790. PMID: 41614309, PMCID: PMC13055448, DOI: 10.1161/jaha.125.044790.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAortic Aneurysm, ThoracicBlood Vessel ProsthesisBlood Vessel Prosthesis ImplantationComputed Tomography AngiographyComputer SimulationEndovascular Aneurysm RepairEndovascular ProceduresFemaleGraft Occlusion, VascularHemodynamicsHumansMaleMiddle AgedModels, CardiovascularPatient-Specific ModelingProsthesis DesignRetrospective StudiesRisk FactorsStentsTreatment OutcomeConceptsTime-averaged wall shear stressRigid-walled simulationsComputational flow simulationsWall shear stressShear stressFlow simulationsEndovascular aneurysm repairIndividual geometryBoundary conditionsSurface areaAneurysm repairAssociated with occlusionBranch occlusionSimulationPostoperative areaIV thoracoabdominal aortic aneurysmsOcclusion probabilityRenal branch occlusionSimVascularThoracoabdominal aortic aneurysmsMesenteric branchesBranch vessel occlusionReceiver operating characteristic curvePoria cocos as a Functional Food for Diabetes and Diabetes‐Related Foot Ulcers
Lee Y, Kuo T, Yang G, Yang W. Poria cocos as a Functional Food for Diabetes and Diabetes‐Related Foot Ulcers. 2026, 2: 30-38. DOI: 10.1002/agf2.70010.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2025
Interrogating the Impact of Bone Metastasis-associated Myelopoiesis Skewing in Tumor Progression 4801
Chen H, Su T, Lin J, Yeh T, Bandara T, Chen T, Hsiao P, Yang W. Interrogating the Impact of Bone Metastasis-associated Myelopoiesis Skewing in Tumor Progression 4801. The Journal Of Immunology 2025, 214 DOI: 10.1093/jimmun/vkaf283.2423.Peer-Reviewed Original ResearchMyelopoietic progenitorsImmune signaturesProstate cancerCancer cellsAssociated with relapseTerminal differentiationMultiple immune organsColon cancer cellsAmeliorate disease progressionBone-metastaticBM chimerasPCa patientsMyeloid cellsTumor cellsBone microenvironmentLy6Chi monocytesDisease progressionProtein expressionNiche factorsLate stageSiglec-FImmune organsProgenitorsTumorBoneNatural Products Targeting Protein Disulfide Isomerases: New Frontiers for Diabetes, Cancer, and Coagulation
Lee Y, Ortega C, Kuo T, Yang G, Yang W. Natural Products Targeting Protein Disulfide Isomerases: New Frontiers for Diabetes, Cancer, and Coagulation. Food Frontiers 2025, 6: 2165-2181. DOI: 10.1002/fft2.70059.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsPancreatic β-cell apoptosis caused by apolipoprotein C3-rich low-density lipoprotein is attenuated by kansuinine A through oxidative stress inhibition
Lulji Taraqaz B, Hsu Y, Tsai P, Li Y, Chen F, Yang W, Shen M. Pancreatic β-cell apoptosis caused by apolipoprotein C3-rich low-density lipoprotein is attenuated by kansuinine A through oxidative stress inhibition. Biomedicine & Pharmacotherapy 2025, 187: 118066. PMID: 40262236, DOI: 10.1016/j.biopha.2025.118066.Peer-Reviewed Original ResearchConceptsB cell apoptosisRat pancreatic B-cellsLow-density lipoproteinPathway analysisSignaling pathwayOxidative stressApoptosisImproved cell viabilityRIN-m5FB cellsLectin-like oxidized low-density lipoprotein receptor-1Pancreatic B-cellsHigh-fat dietCell viabilityInsulin toleranceAntiapoptotic propertiesKansuinine AMitigated apoptosisMechanism of actionMolecular dockingStress inhibitionPathwayLow-density lipoprotein receptor-1Improved glucoseHigh-fat
2013
Myeloid-derived Suppressor Cells in Autoimmune Diabetes: Their Antidiabetic Potential and Mechanism
Wen-Chin Y. Myeloid-derived Suppressor Cells in Autoimmune Diabetes: Their Antidiabetic Potential and Mechanism. Journal Of Diabetes & Metabolism 2013 DOI: 10.4172/2155-6156.s12-004.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMyeloid-derived suppressor cellsMechanism of myeloid-derived suppressor cellSuppressor cellsAutoimmune diabetesImmune interventionTolerogenic mechanismsImmune responseAutoreactive immune responsesSS cellsPancreatic ss-cellsFatal complicationReplacement therapySupportive medicationsDiabetesInsulin injectionSignaling pathwayInsulinAIDS developmentCellsAntidiabetic potentialComplicationsInsufficiency/deficiency
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