Oleanolic Acid Promotes Neuronal Differentiation and Histone Deacetylase 5 Phosphorylation in Rat Hippocampal Neurons
Jo HR, Wang SE, Kim YS, Lee CH, Son H. Oleanolic Acid Promotes Neuronal Differentiation and Histone Deacetylase 5 Phosphorylation in Rat Hippocampal Neurons. Molecules And Cells 2017, 40: 485-494. PMID: 28681592, PMCID: PMC5547218, DOI: 10.14348/molcells.2017.0034.Peer-Reviewed Original ResearchMeSH KeywordsActive Transport, Cell NucleusAnimalsCell DifferentiationCell NucleusDendritic SpinesGene Expression RegulationHippocampusHistone DeacetylasesMEF2 Transcription FactorsNeural Stem CellsNeuritesNeuronsOleanolic AcidPhosphorylationProtein Kinase CRats, Sprague-DawleySubcellular FractionsSynapsesConceptsRat hippocampal neural progenitor cellsEffects of OAHippocampal neural progenitor cellsNeuronal differentiationOA derivativesOleanolic acidHDAC5 phosphorylationHistone deacetylase 5 (HDAC5) phosphorylationRat hippocampal neuronsNeural progenitor cellsPromotes Neuronal DifferentiationHistone deacetylase 5Neurotrophic effectsHippocampal neuronsNeurological drugsProgenitor cellsNeural differentiationNeuronsPresent studyTarget genesExpressionFurther researchGene expressionPhosphorylationDifferentiation