Lingjuan Hong, PhD
Associate Research Scientist in GeneticsDownloadHi-Res Photo
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Research at a Glance
Yale Co-Authors
Frequent collaborators of Lingjuan Hong's published research.
Publications Timeline
A big-picture view of Lingjuan Hong's research output by year.
Arya Mani, MD, FACC, FAHA
Sameet Mehta, PhD
Curt Scharfe, MD, PhD, FACMG
David van Dijk, PhD, MSc, BSc
James Noonan, PhD
Renato Polimanti, PhD, MSc
16Publications
832Citations
Publications
2023
A systems biology approach identifies the role of dysregulated PRDM6 in the development of hypertension
Gunawardhana K, Hong L, Rugira T, Kucharczak J, Mehta S, Karunamuni D, Cabera-Mendoza B, Scharfe C, Polimanti R, Noonan J, Mani A. A systems biology approach identifies the role of dysregulated PRDM6 in the development of hypertension. Journal Of Clinical Investigation 2023, 133: e160036. PMID: 36602864, PMCID: PMC9927944, DOI: 10.1172/jci160036.Peer-Reviewed Original ResearchCitationsAltmetric
2022
Prdm6 controls heart development by regulating neural crest cell differentiation and migration
Hong L, Li N, Gasque V, Mehta S, Ye L, Wu Y, Li J, Gewies A, Ruland J, Hirschi KK, Eichmann A, Hendry C, van Dijk D, Mani A. Prdm6 controls heart development by regulating neural crest cell differentiation and migration. JCI Insight 2022, 7: e156046. PMID: 35108221, PMCID: PMC8876496, DOI: 10.1172/jci.insight.156046.Peer-Reviewed Original ResearchCitationsAltmetric
2018
Cathepsin B inhibition ameliorates leukocyte‐endothelial adhesion in the BTBR mouse model of autism
Wang H, Yin Y, Gong D, Hong L, Wu G, Jiang Q, Wang C, Blinder P, Long S, Han F, Lu Y. Cathepsin B inhibition ameliorates leukocyte‐endothelial adhesion in the BTBR mouse model of autism. CNS Neuroscience & Therapeutics 2018, 25: 476-485. PMID: 30328295, PMCID: PMC6488924, DOI: 10.1111/cns.13074.Peer-Reviewed Original ResearchCitationsAltmetricEndothelial GPR124 Exaggerates the Pathogenesis of Atherosclerosis by Activating Inflammation
Gong D, Zhang Y, Chen D, Hong L, Han F, Liu Q, Jiang J, Lu Y. Endothelial GPR124 Exaggerates the Pathogenesis of Atherosclerosis by Activating Inflammation. Cellular Physiology And Biochemistry 2018, 45: 547-557. PMID: 29402834, DOI: 10.1159/000487032.Peer-Reviewed Original ResearchCitationsAltmetricMeSH KeywordsAnimalsAntigens, CDAntigens, Differentiation, MyelomonocyticAtherosclerosisCaspase 1CholesterolCholesterol, LDLDiet, High-FatDisease Models, AnimalHumansInflammationMiceMice, Inbred C57BLMice, TransgenicMyocytes, Smooth MuscleNLR Family, Pyrin Domain-Containing 3 ProteinPeroxynitrous AcidPlasmidsReceptors, G-Protein-CoupledSinus of Valsalva
2017
BNGR-A25L and -A27 are two functional G protein–coupled receptors for CAPA periviscerokinin neuropeptides in the silkworm Bombyx mori
Shen Z, Chen Y, Hong L, Cui Z, Yang H, He X, Shi Y, Shi L, Han F, Zhou N. BNGR-A25L and -A27 are two functional G protein–coupled receptors for CAPA periviscerokinin neuropeptides in the silkworm Bombyx mori. Journal Of Biological Chemistry 2017, 292: 16554-16570. PMID: 28842502, PMCID: PMC5633119, DOI: 10.1074/jbc.m117.803445.Peer-Reviewed Original ResearchCitationsAltmetric
2015
Novel 1‑Phenyl-3-hydroxy-4-pyridinone Derivatives as Multifunctional Agents for the Therapy of Alzheimer’s Disease
Sheng R, Tang L, Jiang L, Hong L, Shi Y, Zhou N, Hu Y. Novel 1‑Phenyl-3-hydroxy-4-pyridinone Derivatives as Multifunctional Agents for the Therapy of Alzheimer’s Disease. ACS Chemical Neuroscience 2015, 7: 69-81. PMID: 26479744, DOI: 10.1021/acschemneuro.5b00224.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsCitationsAltmetricVisualizing Peroxynitrite Fluxes in Endothelial Cells Reveals the Dynamic Progression of Brain Vascular Injury
Li X, Tao R, Hong L, Cheng J, Jiang Q, Lu Y, Liao M, Ye W, Lu N, Han F, Hu Y, Hu Y. Visualizing Peroxynitrite Fluxes in Endothelial Cells Reveals the Dynamic Progression of Brain Vascular Injury. Journal Of The American Chemical Society 2015, 137: 12296-12303. PMID: 26352914, DOI: 10.1021/jacs.5b06865.Peer-Reviewed Original ResearchCitationsP2RX7 sensitizes Mac-1/ICAM-1-dependent leukocyte-endothelial adhesion and promotes neurovascular injury during septic encephalopathy
Wang H, Hong L, Huang J, Jiang Q, Tao R, Tan C, Lu N, Wang C, Ahmed M, Lu Y, Liu Z, Shi W, Lai E, Wilcox C, Han F. P2RX7 sensitizes Mac-1/ICAM-1-dependent leukocyte-endothelial adhesion and promotes neurovascular injury during septic encephalopathy. Cell Research 2015, 25: 674-690. PMID: 25998681, PMCID: PMC4456628, DOI: 10.1038/cr.2015.61.Peer-Reviewed Original ResearchCitationsAltmetricValproic Acid Influences MTNR1A Intracellular Trafficking and Signaling in a β-Arrestin 2-Dependent Manner
Hong L, Jiang Q, Long S, Wang H, Zhang L, Tian Y, Wang C, Cao J, Tao R, Huang J, Liao M, Lu Y, Fukunaga K, Zhou N, Han F. Valproic Acid Influences MTNR1A Intracellular Trafficking and Signaling in a β-Arrestin 2-Dependent Manner. Molecular Neurobiology 2015, 53: 1237-1246. PMID: 25613019, DOI: 10.1007/s12035-014-9085-y.Peer-Reviewed Original ResearchCitationsAltmetricMeSH KeywordsAnimalsbeta-ArrestinsCyclic AMP-Dependent Protein KinasesEndocytosisExtracellular Signal-Regulated MAP KinasesFluorescence Resonance Energy TransferHEK293 CellsHumansIntracellular SpaceMelatoninMicePhosphorylationProtein BindingProtein Transportrab GTP-Binding ProteinsReceptor, Melatonin, MT1Signal TransductionValproic Acid
2014
Nitrosative Stress Induces Peroxiredoxin 1 Ubiquitination During Ischemic Insult via E6AP Activation in Endothelial Cells Both In Vitro and In Vivo
Tao R, Wang H, Hong L, Huang J, Lu Y, Liao M, Ye W, Lu N, Zhu D, Huang Q, Fukunaga K, Lou Y, Shoji I, Wilcox C, Lai E, Han F. Nitrosative Stress Induces Peroxiredoxin 1 Ubiquitination During Ischemic Insult via E6AP Activation in Endothelial Cells Both In Vitro and In Vivo. Antioxidants & Redox Signaling 2014, 21: 1-16. PMID: 24295341, PMCID: PMC4048580, DOI: 10.1089/ars.2013.5381.Peer-Reviewed Original ResearchCitationsAltmetric
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