Plasmodium yoelii Vitamin B5 Pantothenate Transporter Candidate is Essential for Parasite Transmission to the Mosquito
Hart RJ, Lawres L, Fritzen E, Mamoun C, Aly AS. Plasmodium yoelii Vitamin B5 Pantothenate Transporter Candidate is Essential for Parasite Transmission to the Mosquito. Scientific Reports 2014, 4: 5665. PMID: 25012929, PMCID: PMC4092334, DOI: 10.1038/srep05665.Peer-Reviewed Original ResearchConceptsSexual blood stage developmentYeast cellsLife cycle stagesNon-photosynthetic cellsParasite plasma membraneMultiple parasite life cycle stagesParasite life cycle stagesBlood stage developmentPantothenate transportGene-targeting techniquesHuman malaria parasiteCycle stagesFunctional complementationPAT inhibitorsPlasma membraneSporozoite formationTransporter candidatesVivo functionOocyst stageP. falciparuminParasite transmissionPantothenate concentrationPantothenate uptakeCoenzyme AMalaria parasites