2023
Baseline platelet serotonin in a multi-site treatment study of depression in veterans administration patients: Distribution and effects of demographic variables and serotonin reuptake inhibitors
Anderson G, Ramsey C, Lynch K, Gelernter J, Oslin D. Baseline platelet serotonin in a multi-site treatment study of depression in veterans administration patients: Distribution and effects of demographic variables and serotonin reuptake inhibitors. Journal Of Affective Disorders 2023, 327: 368-377. PMID: 36754092, DOI: 10.1016/j.jad.2023.02.017.Peer-Reviewed Original ResearchMeSH KeywordsCross-Sectional StudiesDemographyDepressionFemaleHumansMaleMembrane Transport ProteinsSelective Serotonin Reuptake InhibitorsSerotoninSerotonin and Noradrenaline Reuptake InhibitorsUnited StatesUnited States Department of Veterans AffairsConceptsReuptake inhibitorsVeterans Administration patientsTreatment studiesSubset of patientsNorepinephrine reuptake inhibitorsCross-sectional studyEffect of ageDose adjustmentAfrican American individualsDemographic variablesMean plateletDrug exposurePlatelet serotoninSerotonin valuesPatientsClinical implicationsHealth recordsMale groupSSRIsDepressionPlateletsEuropean AmericansInhibitorsSex differencesGroup means
2006
Serotonin transporter gene promoter polymorphism predicts SSRI response in generalized social anxiety disorder
Stein MB, Seedat S, Gelernter J. Serotonin transporter gene promoter polymorphism predicts SSRI response in generalized social anxiety disorder. Psychopharmacology 2006, 187: 68-72. PMID: 16525856, DOI: 10.1007/s00213-006-0349-8.Peer-Reviewed Original ResearchAdultAnxiety DisordersFemaleGenotypeHumansMaleMiddle AgedPolymorphism, GeneticPromoter Regions, GeneticSelective Serotonin Reuptake InhibitorsSerotonin Plasma Membrane Transport Proteins
1998
Tryptophan hydroxylase genotype is associated with impulsive‐aggression measures: a preliminary study
New A, Gelernter J, Yovell Y, Trestman R, Nielsen D, Silverman J, Mitropoulou V, Siever L. Tryptophan hydroxylase genotype is associated with impulsive‐aggression measures: a preliminary study. American Journal Of Medical Genetics 1998, 81: 13-17. PMID: 9514581, DOI: 10.1002/(sici)1096-8628(19980207)81:1<13::aid-ajmg3>3.0.co;2-o.Peer-Reviewed Original ResearchMeSH KeywordsAdultAggressionFemaleFenfluramineGenotypeHumansImpulsive BehaviorMaleProlactinSelective Serotonin Reuptake InhibitorsSerotoninTryptophan HydroxylaseConceptsProlactin responseTPH genotypeTryptophan hydroxylase genotypePersonality disorder patientsImpulsive aggressive behaviorBuss-Durkee Hostility InventoryMale patientsCaucasian patientsDisorder patientsFenfluraminePatientsImpulsive aggressionPersonality disorderHostility InventoryPreliminary studyBDHI scoresGenotypesResponse