2011
Induced pluripotent stem cells for neural tissue engineering
Wang A, Tang Z, Park IH, Zhu Y, Patel S, Daley GQ, Li S. Induced pluripotent stem cells for neural tissue engineering. Biomaterials 2011, 32: 5023-5032. PMID: 21514663, PMCID: PMC3100451, DOI: 10.1016/j.biomaterials.2011.03.070.Peer-Reviewed Original ResearchConceptsEmbryonic stem cellsTissue engineeringNeural tissue engineeringPluripotent stem cellsNanofibrous tubular scaffoldsRegenerative medicine applicationsStem cellsTissue-engineered nerve conduitNeural crest stem cellsDifferentiation of iPSCsTeratoma formationMedicine applicationsGreat promiseTremendous potentialIPSC differentiationEctodermal lineagesTubular scaffoldsMultipotent neural crest stem cellsCell therapyEngineeringHuman iPSCDifferent cell linesAccelerated regenerationScaffoldsIPSCs
2006
In vitro generation of germ cells from murine embryonic stem cells
West JA, Park IH, Daley GQ, Geijsen N. In vitro generation of germ cells from murine embryonic stem cells. Nature Protocols 2006, 1: 2026-2036. PMID: 17487192, DOI: 10.1038/nprot.2006.303.Peer-Reviewed Original ResearchConceptsPutative primordial germ cellsEmbryonic stem cellsMurine embryonic stem cellsGerm cellsPrimordial germ cellsGerm cell developmentEmbryoid body differentiationHaploid male gametesStem cellsImprint erasureEpigenetic phenomenaGamete formationHaploid cellsGamete developmentMature gametesMale gametesStages of differentiationDifferentiation systemBody differentiationGerm layersCell developmentAggregates of cellsSpontaneous differentiationTeratoma formationCell allocation