2025
A Bayesian approach to correcting the attenuation bias of regression using polygenic risk score
Zhou G, Qie X, Zhao H. A Bayesian approach to correcting the attenuation bias of regression using polygenic risk score. Genetics 2025, 229: iyaf018. PMID: 39891671, PMCID: PMC12168083, DOI: 10.1093/genetics/iyaf018.Peer-Reviewed Original ResearchConceptsPolygenic risk scoresRisk scoreEstimation of regression coefficientsBayesian approachMeasurement error modelEstimation of coefficientsCoverage probabilityBayesian measurement error modelsAttenuation biasCredible intervalsCoefficient estimatesUK BiobankLogistic regressionMeasurement errorRegression coefficientsRegression modelsComplex traitsRegression analysisScoresEstimationError modelRegressionBiobankErrorCovariates
2011
Bayesian hierarchical modeling for signaling pathway inference from single cell interventional data
Luo R, Zhao H. Bayesian hierarchical modeling for signaling pathway inference from single cell interventional data. The Annals Of Applied Statistics 2011, 5: 725-745. PMID: 22162986, PMCID: PMC3233205, DOI: 10.1214/10-aoas425.Peer-Reviewed Original ResearchMarkov chain Monte CarloReal data analysisBayesian hierarchical modeling frameworkHierarchical modelingHierarchical modeling frameworkBayesian hierarchical modelingStatistical inferencePosterior distributionMonte CarloNetwork sparsitySimulation studyIntrinsic noiseModeling frameworkMeasurement errorInterventional dataInferenceMultiple protein activitiesPathway inferenceCarloModelingInterventional experimentsSuch dataSparsityData analysisNoise
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