Ring Chromosome 21
Zhang H, Chai H. Ring Chromosome 21. 2024, 287-300. DOI: 10.1007/978-3-031-47530-6_25.Peer-Reviewed Original ResearchChromosomal microarray analysisCongenital anomaliesAcute leukemiaFluorescence in situ hybridizationTreatment of congenital anomaliesIncreased risk of miscarriageMultiple congenital anomaliesRisk of miscarriageBone marrow cellsEvaluation of infertilityAdult male patientsAdult female patientsRing chromosome 21Chromosome 21Spectrum of phenotypesGenomic imbalancesCraniofacial dysmorphismFemale patientsMale patientsMarrow cellsChromosome analysisClinical managementIncreased riskDevelopmental delayPatientsCopy number variation of metallothionein 1 (MT1) associates with MT1X isoform expression and the overall survival of hepatocellular carcinoma patients in Guangxi
Xu P, Al-Anesi M, Huang M, Wu S, Ge Y, Chai H, Li P, Hu Q. Copy number variation of metallothionein 1 (MT1) associates with MT1X isoform expression and the overall survival of hepatocellular carcinoma patients in Guangxi. Gene Reports 2024, 34: 101889. DOI: 10.1016/j.genrep.2024.101889.Peer-Reviewed Original ResearchHepatocellular carcinoma patientsOverall survivalHepatocellular carcinoma diagnosisCopy number variationsHepatocellular carcinomaCancer tissuesDown-regulationMetallothionein-1Survival of hepatocellular carcinoma patientsEffects of copy number variationPredictors of OSOverall survival of hepatocellular carcinoma patientsMetallothionein-1 geneMetallothionein-1 proteinSimultaneous down-regulationCarcinoma patientsACGH analysisTumor-suppressive effectsNumber variationsIsoform expressionTranslational levelPatientsCancerResults of RT-qPCRGenes