2013
Nathans, Daniel
DiMaio D, Kelly T. Nathans, Daniel. 2013, 6-7. DOI: 10.1016/b978-0-12-374984-0.01019-6.Peer-Reviewed Original Research
1993
Inhibition of cervical carcinoma cell line proliferation by the introduction of a bovine papillomavirus regulatory gene
Hwang E, Riese D, Settleman J, Nilson L, Honig J, Flynn S, DiMaio D. Inhibition of cervical carcinoma cell line proliferation by the introduction of a bovine papillomavirus regulatory gene. Journal Of Virology 1993, 67: 3720-3729. PMID: 8389903, PMCID: PMC237735, DOI: 10.1128/jvi.67.7.3720-3729.1993.Peer-Reviewed Original ResearchConceptsBPV E2 proteinGene expressionCervical carcinoma cell linesRegulatory genesHPV gene expressionCarcinoma cell linesCell linesE2 proteinHeLa cellsConsequence of abrogationP53 tumor suppressor proteinHPV18 E6Tumor suppressor proteinE2 geneDestabilization of p53HT-3 cellsGrowth inhibitionBPV E2Simian virus 40Suppressor proteinEpithelial cell lineHuman papillomavirus E6Cell cycleGenesS phase
1980
Cold-sensitive regulatory mutants of simian virus 40
DiMaio D, Nathans D. Cold-sensitive regulatory mutants of simian virus 40. Journal Of Molecular Biology 1980, 140: 129-142. PMID: 6251230, DOI: 10.1016/0022-2836(80)90359-9.Peer-Reviewed Original ResearchConceptsRegulatory segmentBase substitutionsBglI siteWild-type plaquesProtein-coding sequencesProtein-nucleic acid interactionsCold-sensitive mutantsOrigin of replicationSet of mutantsSimian virus 40 mutantsDNA polymerase IBase substitution mutationsRNA processingRegulatory mutantsDNA replicationReplication originsViable mutantsSimian virus 40Small plaquesMutational alterationsWild-type virusPolymerase IMutantsRegulatory phenomenaSubstitution mutations
1979
Constructed Mutants of Simian Virus 40
Shortle D, Pipas J, Lazarowitz S, DiMaio D, Nathans D. Constructed Mutants of Simian Virus 40. Genetic Engineering: Principles And Methods 1979, 73-92. DOI: 10.1007/978-1-4615-7072-1_5.Peer-Reviewed Original ResearchGenetic analysisDNA moleculesNucleic acid biochemistryRegulatory elementsSimian virus 40Such mutantsDNA sequencesNucleotide sequenceRandom mutagenesisPhenotype selectionGenomePhysiological defectsSpontaneous mutationsMutantsSpecific base changesViral genomeBase changesRestriction endonucleasesRestriction sitesMutant virusCleavage mapSite specificitySpecific sitesSequenceRecent advances