Multi-frequency impedance sensing for detection and sizing of DNA fragments
Sui J, Gandotra N, Xie P, Lin Z, Scharfe C, Javanmard M. Multi-frequency impedance sensing for detection and sizing of DNA fragments. Scientific Reports 2021, 11: 6490. PMID: 33753781, PMCID: PMC7985362, DOI: 10.1038/s41598-021-85755-9.Peer-Reviewed Original ResearchConceptsTarget molecule bindsComplex biological samplesElectronic biosensorsNon-target materialsProbe selectivityAnalytical performanceMolecules bindBiological samplesReaction productsDifferent lengthsDNA moleculesDNA detectionMicrofluidic chipNonspecific bindingFmolElectronic signalsParamagnetic beadsImpedance sensorBeadsBiosensorDNA concentrationDNA fragmentsSelectivityProbePolymerase chain reaction products