1989
Mitochondrial heat-shock protein hsp60 is essential for assembly of proteins imported into yeast mitochondria
Cheng M, Hartl F, Martin J, Pollock R, Kalousek F, Neuper W, Hallberg E, Hallberg R, Horwich A. Mitochondrial heat-shock protein hsp60 is essential for assembly of proteins imported into yeast mitochondria. Nature 1989, 337: 620-625. PMID: 2645524, DOI: 10.1038/337620a0.Peer-Reviewed Original Research
1988
Meiotic expression of human ornithine transcarbamylase in the testes of transgenic mice.
Kelley K, Chamberlain J, Nolan J, Horwich A, Kalousek F, Eisenstadt J, Herrup K, Rosenberg L. Meiotic expression of human ornithine transcarbamylase in the testes of transgenic mice. Molecular And Cellular Biology 1988, 8: 1821-1825. PMID: 2837657, PMCID: PMC363346, DOI: 10.1128/mcb.8.4.1821.Peer-Reviewed Original ResearchConceptsHuman ornithine transcarbamylaseFusion geneBase pairsProtein-coding sequencesMale germ cellsOrnithine transcarbamylaseMeiotic expressionRegulatory sequencesRegulatory regionsTransgenic micePachytene stageMouse metallothioneinTransgenic animalsGerm cellsGenesKilobasesTransgene expressionSequenceExpressionTranscarbamylaseMeiosisTetraploid
1983
Molecular cloning of the cDNA coding for rat ornithine transcarbamoylase.
Horwich A, Kraus J, Williams K, Kalousek F, Konigsberg W, Rosenberg L. Molecular cloning of the cDNA coding for rat ornithine transcarbamoylase. Proceedings Of The National Academy Of Sciences Of The United States Of America 1983, 80: 4258-4262. PMID: 6576335, PMCID: PMC384016, DOI: 10.1073/pnas.80.14.4258.Peer-Reviewed Original ResearchConceptsOrnithine transcarbamoylaseSequential Edman analysesCDNA probeMitochondrial matrix enzymeInsertion of cDNAAmino acid residuesConsecutive amino acid residuesCarboxyl-terminal portionCytoplasmic polysomesMolecular cloningCDNA clonesEdman analysisDifferential colony hybridizationTranslation assaysX chromosomeCDNA codingMatrix enzymeEnzyme subunitMessenger speciesAcid residuesSequence presentPolysome immunoadsorptionIdentical subunitsColony hybridizationEscherichia coli