1995
CEPH Consortium Map of Chromosome 14
Cox D, Billingsley G, Bale A, Donis-Keller H, Edwards J, Litt M, Mcbride W, Persichetti F, Spurr N, Weber J, Weissenbach J, White R. CEPH Consortium Map of Chromosome 14. Cytogenetic And Genome Research 1995, 69: 175-178. PMID: 7698005, DOI: 10.1159/000133955.Peer-Reviewed Original ResearchChromosome MappingChromosomes, Human, Pair 14Genetic LinkageGenetic MarkersHumansPolymorphism, Restriction Fragment Length
1994
Localization of the gene for the nevoid basal cell carcinoma syndrome.
Goldstein A, Stewart C, Bale A, Bale S, Dean M. Localization of the gene for the nevoid basal cell carcinoma syndrome. American Journal Of Human Genetics 1994, 54: 765-73. PMID: 7909984, PMCID: PMC1918262.Peer-Reviewed Original ResearchMeSH KeywordsAllelesBasal Cell Nevus SyndromeChromosome MappingChromosomes, Human, Pair 9DNA, SatelliteFemaleGenetic LinkageGenetic MarkersHumansLod ScoreMalePedigreePolymerase Chain ReactionPolymorphism, Restriction Fragment Length
1992
Developmental defects in gorlin syndrome related to a putative tumor suppressor gene on chromosome 9
Gailani M, Bale S, Leffell D, DiGiovanna J, Peck G, Poliak S, Drum M, Pastakia B, McBride O, Kase R, Greene M, Mulvihill J, Bale A. Developmental defects in gorlin syndrome related to a putative tumor suppressor gene on chromosome 9. Cell 1992, 69: 111-117. PMID: 1348213, DOI: 10.1016/0092-8674(92)90122-s.Peer-Reviewed Original ResearchMeSH KeywordsBasal Cell Nevus SyndromeChromosomes, Human, Pair 9FemaleGenes, Tumor SuppressorGenetic LinkageHeterozygoteHumansMaleMutationPedigreePolymorphism, Restriction Fragment LengthConceptsBasal cell carcinomaSporadic basal cell carcinomasCell carcinomaLoss of heterozygosityGorlin syndromeHereditary tumorsTumor suppressor geneHereditary basal cell carcinomasMultiple congenital anomaliesSuppressor geneAutosomal dominant disorderOvarian fibromaCongenital anomaliesCarcinomaGermline mutationsHereditary disorderPutative tumor suppressor geneDevelopmental defectsSyndromeGorlin syndrome geneDominant disorderAllelic lossGenetic linkage studiesTumorsTumor suppressor
1991
Localization of a DNA segment encompassing four tRNA genes to human chromosome 14q11 and its use as an anchor locus for linkage analysis
Mitchell A, Bale A, Wang-ge M, Yi H, White R, Pirtle R, McBride O. Localization of a DNA segment encompassing four tRNA genes to human chromosome 14q11 and its use as an anchor locus for linkage analysis. Genomics 1991, 11: 1063-1070. PMID: 1686015, DOI: 10.1016/0888-7543(91)90033-b.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceChromosome MappingChromosomes, Human, Pair 14FemaleGenetic LinkageGenetic MarkersHumansMaleMolecular Sequence DataMultigene FamilyNucleic Acid HybridizationPolymorphism, Restriction Fragment LengthRestriction MappingRNA, TransferRNA, Transfer, LeuRNA, Transfer, ProRNA, Transfer, ThrConceptsT cell receptor alphaTRNA genesAnchor lociChromosomal locationHuman/rodent somatic cell hybridsRodent somatic cell hybridsLinkage analysisChromosome 14Human tRNA genesSomatic cell hybridsGenetic linkage analysisTRNA clusterMYH7 locusGene clusterGenomic fragmentCell hybridsCEPH pedigreesChromosome 14q11Southern analysisDNA segmentsGene locusAnonymous probesLociInformative membersSitu hybridizationA contiguous linkage map of chromosome 13q with 39 distinct loci separated on average by 5.1 centimorgans
Bowcock A, Farrer L, Hebert J, Bale A, Cavalli-Sforza L. A contiguous linkage map of chromosome 13q with 39 distinct loci separated on average by 5.1 centimorgans. Genomics 1991, 11: 517-529. PMID: 1685473, DOI: 10.1016/0888-7543(91)90058-m.Peer-Reviewed Original ResearchMeSH KeywordsChromosome MappingChromosomes, Human, Pair 13DNA ProbesFemaleGenetic LinkageHumansMalePlasmidsPolymorphism, Restriction Fragment LengthRecombination, GeneticSex FactorsConceptsLinkage mapDistinct lociChromosome 13qExcess of recombinationMean genetic distanceGenetic distanceAlpha-satellite probeFemale recombinationAdjacent lociFamily DNAChromosomal armsDisease locusCEPH family DNAsLociChromosome 13Enzyme combinationsComplete mapAdditional markersRecombinationCentimorgansGenesFold excessDNASequenceProbePRAD1, a candidate BCL1 oncogene: mapping and expression in centrocytic lymphoma.
Rosenberg C, Wong E, Petty E, Bale A, Tsujimoto Y, Harris N, Arnold A. PRAD1, a candidate BCL1 oncogene: mapping and expression in centrocytic lymphoma. Proceedings Of The National Academy Of Sciences Of The United States Of America 1991, 88: 9638-9642. PMID: 1682919, PMCID: PMC52773, DOI: 10.1073/pnas.88.21.9638.Peer-Reviewed Original ResearchHuman CYP1A1 gene: cosegregation of the enzyme inducibility phenotype and an RFLP.
Petersen D, McKinney C, Ikeya K, Smith H, Bale A, McBride O, Nebert D. Human CYP1A1 gene: cosegregation of the enzyme inducibility phenotype and an RFLP. American Journal Of Human Genetics 1991, 48: 720-5. PMID: 1707592, PMCID: PMC1682951.Peer-Reviewed Original ResearchTight linkage of the human c-erbAβ gene with the syndrome of generalized thyroid hormone resistance is present in multiple kindreds
Fein H, Burman K, Djuh Y, Usala S, Bale A, Weintraub B, Smallridge R. Tight linkage of the human c-erbAβ gene with the syndrome of generalized thyroid hormone resistance is present in multiple kindreds. Journal Of Endocrinological Investigation 1991, 14: 219-223. PMID: 1677017, DOI: 10.1007/bf03346792.Peer-Reviewed Original ResearchMeSH KeywordsBase SequenceChromosome MappingDeoxyribonuclease BamHIDeoxyribonucleases, Type II Site-SpecificDrug ResistanceErbB ReceptorsGenetic LinkageHumansMolecular Sequence DataMutationPedigreePolymorphism, Restriction Fragment LengthProto-Oncogene ProteinsReceptors, Thyroid HormoneSyndromeThyroid DiseasesThyroid HormonesThyrotropinThyroxineTriiodothyronineAllelic loss on chromosome 11 in hereditary and sporadic tumors related to familial multiple endocrine neoplasia type 1.
Bale A, Norton J, Wong E, Fryburg J, Maton P, Oldfield E, Streeten E, Aurbach G, Brandi M, Friedman E. Allelic loss on chromosome 11 in hereditary and sporadic tumors related to familial multiple endocrine neoplasia type 1. Cancer Research 1991, 51: 1154-7. PMID: 1671755.Peer-Reviewed Original ResearchMeSH KeywordsAdenoma, Islet CellAllelesCarcinoma, BronchogenicChromosomes, Human, Pair 11Genes, Tumor SuppressorHumansMultiple Endocrine NeoplasiaPancreatic NeoplasmsPituitary NeoplasmsPolymorphism, Restriction Fragment LengthConceptsFamilial multiple endocrine neoplasia type 1Multiple endocrine neoplasia type 1Anterior pituitary tumorsPancreatic islet tumorsIslet tumorsPituitary tumorsAllelic lossType 1Autosomal dominant disorderMalignant gastrinomaBronchial carcinoidParathyroid glandsParathyroid tumorsAnterior pituitaryLoss of heterozygosityTumorsPancreatic isletsSporadic tumorsDominant disorderMEN1 genePatientsRestriction fragment length polymorphismFragment length polymorphismHomozygous inactivationInformative restriction fragment length polymorphisms
1989
Six RFLPs for human T cell receptor α (TCRA) on chromosome 14
Mitchell A, Bale A, Mak T, McBride O. Six RFLPs for human T cell receptor α (TCRA) on chromosome 14. Nucleic Acids Research 1989, 17: 2876-2876. PMID: 2566151, PMCID: PMC317684, DOI: 10.1093/nar/17.7.2876.Peer-Reviewed Original ResearchChromosome MappingChromosomes, Human, Pair 14HumansPolymorphism, GeneticPolymorphism, Restriction Fragment LengthReceptors, Antigen, T-CellReceptors, Antigen, T-Cell, alpha-betaLinkage analysis of multiple endocrine neoplasia type 1 with INT2 and other markers on chromosome 11
Bale S, Bale A, Stewart K, Dachowski L, McBride O, Glaser T, Green J, Mulvihill J, Brandi M, Sakaguchi K, Aurbach G, Marx S. Linkage analysis of multiple endocrine neoplasia type 1 with INT2 and other markers on chromosome 11. Genomics 1989, 4: 320-322. PMID: 2565877, DOI: 10.1016/0888-7543(89)90336-4.Peer-Reviewed Original ResearchMeSH KeywordsChromosomes, Human, Pair 11FemaleGenetic MarkersHumansLod ScoreMaleMultiple Endocrine NeoplasiaPedigreePhosphorylasesPolymorphism, Restriction Fragment LengthConceptsChromosome 11Skeletal muscle glycogen phosphorylasePolymorphic DNA (RAPD) markersMuscle glycogen phosphorylaseSingle large pedigreeDNA markersGene locusFibroblast growth factorBasic fibroblast growth factorMultiple endocrine neoplasia type 1Glycogen phosphorylaseLarge pedigreeGenesLociRecent findingsMultipoint analysisGrowth factorMEN1 geneMarkersINT2PedigreeMEN1 patientsPhosphorylaseType 1
1988
Tight Linkage between the Syndrome of Generalized Thyroid Hormone Resistance and the Human c-erbAβ Gene
Usala S, Bale A, Gesundheit N, Weinberger C, Lash R, Wondisford F, McBride O, Weintraub B. Tight Linkage between the Syndrome of Generalized Thyroid Hormone Resistance and the Human c-erbAβ Gene. Endocrinology 1988, 2: 1217-1220. PMID: 2905763, DOI: 10.1210/mend-2-12-1217.Peer-Reviewed Original ResearchMeSH KeywordsDrug ResistanceGenetic LinkageHumansPedigreePolymorphism, Restriction Fragment LengthProto-Oncogene ProteinsReceptors, Thyroid HormoneSyndromeThyroid DiseasesTriiodothyronineConceptsThyroid hormone receptorGeneralized thyroid hormone resistanceBiological functionsC-erbA beta geneC-erbA genesHormone receptorsMutant phenotypeGene familyC-erbA betaC-erbA alphaRestriction enzyme analysisGene productsChromosome 3Multiple cDNAsThyroid hormone resistanceHuman syndromesTight linkageBeta locusGenesBeta geneNuclear receptorsLarge deletionsHormone resistanceEnzyme analysisCertain kindredsA cDNA probe (PheA12) from the hc-(ERBA) gene on chromosome 3 detects a high frequency RFLP
Bale A, Usala S, Weinberger C, Weintraub B, McBride O. A cDNA probe (PheA12) from the hc-(ERBA) gene on chromosome 3 detects a high frequency RFLP. Nucleic Acids Research 1988, 16: 7756-7756. PMID: 2901070, PMCID: PMC338478, DOI: 10.1093/nar/16.15.7756.Peer-Reviewed Original ResearchChromosome MappingChromosomes, Human, Pair 3DNAHumansPolymorphism, GeneticPolymorphism, Restriction Fragment LengthProto-Oncogene ProteinsA retinoic acid receptor cDNA probe (RAR2) identifies a moderately frequent RFLP on chromosome 17
Bale A, Weinberger C, McBride O. A retinoic acid receptor cDNA probe (RAR2) identifies a moderately frequent RFLP on chromosome 17. Nucleic Acids Research 1988, 16: 7755-7755. PMID: 2901069, PMCID: PMC338477, DOI: 10.1093/nar/16.15.7755.Peer-Reviewed Original ResearchCarrier ProteinsChromosome MappingChromosomes, Human, Pair 17DNAHumansPolymorphism, GeneticPolymorphism, Restriction Fragment LengthReceptors, Retinoic Acid