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Michelle Hampson, PhD

Professor of Radiology and Biomedical Imaging; Director of real-time fMRI

Contact Information

Michelle Hampson, PhD

Mailing Address

  • Radiology & Biomedical Imaging

    PO Box 208042, Yale MRRC, TAC-N121

    New Haven, CT 06520-8042

    United States

Research Summary

We work on the development and application of new functional brain imaging paradigms with a current focus on real-time fMRI neurofeedback. This technique has great potential as a clinical treatment for mental and neurological disorders and is also a powerful perturb-and-measure tool for studying human brain function.

Extensive Research Description

1. We use neurofeedback of real-time fMRI data to train patients with tic disorders, OCD, PTSD, and borderline personality disorder to control clinically relevant brain activity patterns. An important question is whether this training can improve their symptoms.

2. We evaluate changes in resting state functional connectivity between brain areas before and after neurofeedback. This allows us to investigate how neurofeedback alters brain networks. Also, by correlating changes in brain connectivity with symptom changes, we can gain insight into the neural circuitry that gives rise to symptoms.


Research Interests

Magnetic Resonance Imaging; Neurosciences; Obsessive-Compulsive Disorder; Stress Disorders, Post-Traumatic; Video Games; Neurofeedback; Psychiatry and Psychology

Research Image

Selected Publications

Clinical Trials

ConditionsStudy Title
Mental Health & Behavioral ResearchBrain Network Changes Accompanying and Predicting Responses to Pharmacotherapy in OCD
Child Development & Autism; Diseases of the Nervous System; Genetics - Adult; Genetics - Pediatric; Mental Health & Behavioral ResearchGenetic and molecular studies of developmental neuropsychiatric disorders
Diseases of the Nervous System; Mental Health & Behavioral ResearchNeurofeedback of Amygdala Activity for Post-traumatic Stress Disorder (PTSD)
Child Development & Autism; Children's Health; Mental Health & Behavioral ResearchCBT for Anxiety in Children With Autism
Diseases of the Nervous System; Mental Health & Behavioral ResearchBiomarkers of Clinical Subtype and Treatment Response in Obsessive-Compulsive Disorder
Diseases of the Nervous System; Mental Health & Behavioral ResearchNeurofeedback for Obsessive-Compulsive Disorder
Mental Health & Behavioral ResearchStudying the Adult Brain