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INFORMATION FOR

Diseases of the Nervous System, Phase III

Study to Explore the Mechanism of Action of Ocrelizumab and B-Cell Biology in Participants With Relapsing Multiple Sclerosis (RMS)

What is the purpose of this trial?

This is an open-label, multicenter, biomarker study designed to be hypothesis-generating in order to better understand the mechanism of action of ocrelizumab and B-cell biology in RMS. Ocrelizumab will be administered as two intravenous (IV) infusions of 300 milligrams (mg) on Days 1 and 15. Subsequent doses will be given as single 600-mg infusions. Participants will be randomized to receive lumbar puncture (LP) post-treatment at Week 12, 24, or 52.

  • Trial with
    Genentech, Inc.
  • Ages
    18 years - 55 years
  • Gender
    Both
Find out more about who can participate in this trial

Contact Information

For more information about this study, including how to volunteer, contact Erin Longbrake

Help Us Discover!

You can help our team find trials you might be eligible for by creating a volunteer profile in MyChart. To get started, create a volunteer profile, or contact helpusdiscover@yale.edu, or call 877.978.8343 for more information.

Create a volunteer profile

Principal Investigator

  • Last Updated
    07/02/2024
  • Study HIC
    #1602017292

Contact Information

For more information about this study, including how to volunteer, contact Erin Longbrake