2024
Polygenic Risk Scores and Twin Concordance for Schizophrenia and Bipolar Disorder
Song J, Pasman J, Johansson V, Kuja-Halkola R, Harder A, Karlsson R, Lu Y, Kowalec K, Pedersen N, Cannon T, Hultman C, Sullivan P. Polygenic Risk Scores and Twin Concordance for Schizophrenia and Bipolar Disorder. JAMA Psychiatry 2024, 81 PMID: 39196586, PMCID: PMC11359115, DOI: 10.1001/jamapsychiatry.2024.2406.Peer-Reviewed Original ResearchPolygenic risk scoresGenome-wide association studiesSwedish Twin RegistryBipolar disorderCase-control studyTwin concordanceTwin heritabilityLevels of polygenic risk scoreTwin RegistrySwedish national register dataCompare polygenic risk scoresRisk scoreNational register dataHeritable psychiatric disorderAffected co-twinsPairs of twinsPsychosis phenotypeIllness vulnerabilityClinical interviewPsychiatric disordersGenetic liabilityMain OutcomesStructural equation modelingPsychosisSchizophreniaInformation processing style and institutional trust as factors of COVID vaccine hesitancy
Zhao W, Russell C, Jankovsky A, Cannon T, Pittenger C, Pushkarskaya H. Information processing style and institutional trust as factors of COVID vaccine hesitancy. Scientific Reports 2024, 14: 10416. PMID: 38710827, PMCID: PMC11074285, DOI: 10.1038/s41598-024-60788-y.Peer-Reviewed Original ResearchConceptsInformation processing styleIndividual cognitive styleProcessing styleCognitive styleSelf-report measures of personalityMeasures of personalitySelf-report measuresInformation processing capacityPersonality traitsBehavioral tasksStructural equation modelingAuthoritarian submissionEquation modelingProcessing capacityStylePersonsComprehensive assessmentInformation processing capabilitiesPerceptionTrust levelProcessing capabilitiesMultifactorial natureSocio-demographic factorsClinical characteristicsTask
2023
Relations of Lifetime Perceived Stress and Basal Cortisol With Hippocampal Volume Among Healthy Adolescents and Those at Clinical High Risk for Psychosis: A Structural Equation Modeling Approach
Aberizk K, Addington J, Bearden C, Cadenhead K, Cannon T, Cornblatt B, Keshavan M, Mathalon D, Perkins D, Stone W, Tsuang M, Woods S, Walker E, Ku B. Relations of Lifetime Perceived Stress and Basal Cortisol With Hippocampal Volume Among Healthy Adolescents and Those at Clinical High Risk for Psychosis: A Structural Equation Modeling Approach. Biological Psychiatry 2023, 96: 401-411. PMID: 38092185, PMCID: PMC11166888, DOI: 10.1016/j.biopsych.2023.11.027.Peer-Reviewed Original ResearchBilateral hippocampal volumeStructural equation modelingHealthy comparisonsHippocampal volumeBiological sexRelation of ageEquation modelingMultigroup structural equation modelingNorth American Prodrome Longitudinal StudyMeasures of stressNon-human animalsNonspecific risk factorClinical high riskStructural equation modeling approachAdolescent sampleBasal cortisolPerceived stressSmaller hippocampal volumesElevated basal cortisol