2023
Obesity, Growth, Development, Metabolic Disorder, and Insulin Resistance in Pediatrics
Santoro N, Galderisi A, Caprio S. Obesity, Growth, Development, Metabolic Disorder, and Insulin Resistance in Pediatrics. 2023, 608-616. DOI: 10.1201/9781003437673-70.Peer-Reviewed Original ResearchNonalcoholic fatty liver diseaseType 2 diabetesInsulin resistanceAdolescent obesityCardiometabolic risk factorsMajor global health challengeFatty liver diseaseDevelopment of prediabetesGlobal health challengeClinical peculiaritiesFatty liverLiver diseasePediatric obesityRisk factorsPrecocious pubertyMetabolic disordersPathological complicationsObesityHealth challengesPsychosocial conditionsPotential mechanismsDiabetesEarly ageChildrenDyslipidemia
2014
A low disposition index in adolescent offspring of mothers with gestational diabetes: a risk marker for the development of impaired glucose tolerance in youth
Holder T, Giannini C, Santoro N, Pierpont B, Shaw M, Duran E, Caprio S, Weiss R. A low disposition index in adolescent offspring of mothers with gestational diabetes: a risk marker for the development of impaired glucose tolerance in youth. Diabetologia 2014, 57: 2413-2420. PMID: 25168408, DOI: 10.1007/s00125-014-3345-2.Peer-Reviewed Original ResearchConceptsGestational diabetes mellitusImpaired glucose toleranceType 2 diabetesGlucose toleranceNGDM groupDisposition indexInsulin sensitivityNormal glucose toleranceLower disposition indexOral disposition indexBeta-cell functionGestational diabetesDiabetes mellitusUtero exposureObese adolescentsRisk markersGlucose exposureBeta cellsDiabetesAdolescent offspringCell functionSignificant predictorsUteroEarlier inabilityExposure