2022
THC, CBD, and Anxiety: a Review of Recent Findings on the Anxiolytic and Anxiogenic Effects of Cannabis’ Primary Cannabinoids
Lichenstein S. THC, CBD, and Anxiety: a Review of Recent Findings on the Anxiolytic and Anxiogenic Effects of Cannabis’ Primary Cannabinoids. Current Addiction Reports 2022, 9: 473-485. PMID: 38106452, PMCID: PMC10722902, DOI: 10.1007/s40429-022-00450-7.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsRegular cannabis usersAnxiogenic effectsSubstance use disordersImpact anxietyEffects of THCAnxiety disordersCannabis usersClinical populationsHealthy participantsAnxietyTHC administrationLegalization of cannabisUse disordersEffects of CBDSex differencesPurpose of ReviewInSummaryFuture researchRecent FindingsRecent literatureCannabisAnxiolytic effectsRecreational cannabisCBD administrationEarlier findingsMost new studiesTherapeutic potential
2021
Systematic review of structural and functional neuroimaging studies of cannabis use in adolescence and emerging adulthood: evidence from 90 studies and 9441 participants
Lichenstein SD, Manco N, Cope LM, Egbo L, Garrison KA, Hardee J, Hillmer AT, Reeder K, Stern EF, Worhunsky P, Yip SW. Systematic review of structural and functional neuroimaging studies of cannabis use in adolescence and emerging adulthood: evidence from 90 studies and 9441 participants. Neuropsychopharmacology 2021, 47: 1000-1028. PMID: 34839363, PMCID: PMC8938408, DOI: 10.1038/s41386-021-01226-9.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsAdolescent cannabis usersCannabis-related harmsCannabis usersCannabis effectsAdolescent brain functionOngoing brain developmentFunctional neuroimaging studiesEffects of cannabisAdolescent brainNeuroimaging studiesNeural effectsPotential moderatorsNeural alterationsCannabis policy changesReduced perceptionSystematic reviewCannabis useCerebellar regionsAdolescenceBrain functionPreliminary evidenceFuture researchEarly interventionLong-term goalExtant literature