2023
The Brain–Heart Axis: Neuroinflammatory Interactions in Cardiovascular Disease
Hu J, Abdullah A, Nanna M, Soufer R. The Brain–Heart Axis: Neuroinflammatory Interactions in Cardiovascular Disease. Current Cardiology Reports 2023, 25: 1745-1758. PMID: 37994952, PMCID: PMC10908342, DOI: 10.1007/s11886-023-01990-8.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsHeart-brain axisCardiovascular diseaseRenin angiotensin aldosteroneDevelopment of strokeBrain-heart axisAbnormal atrial substrateParasympathetic nervous systemNeuroimmune modulationNeuroinflammatory interactionsNeurogenic inflammationCardioembolic strokeNeurologic insultProinflammatory factorsCardiac dysfunctionAtrial fibrillationAfferent pathwaysAtrial substrateHypothalamus-pituitary axesSpinal injuryCommon disorderCommon conditionProinflammatory signalsNervous systemRecent FindingsAtPrototypical disorder
2009
Heart-brain interactions in mental stress-induced myocardial ischemia
Soufer R, Jain H, Yoon AJ. Heart-brain interactions in mental stress-induced myocardial ischemia. Current Cardiology Reports 2009, 11: 133-140. PMID: 19236829, PMCID: PMC3726062, DOI: 10.1007/s11886-009-0020-1.Peer-Reviewed Original ResearchConceptsMental stress ischemiaStress ischemiaMyocardial ischemiaMental stress-induced myocardial ischemiaStress-induced myocardial ischemiaCoronary artery diseaseCentral nervous systemHeart-brain interactionsArtery diseasePoor prognosisAutonomic balancePathophysiologic underpinningsTreatment strategiesNervous systemIschemiaPsychosocial stressBiobehavioral aspectsBiobehavioral modelBiologic consequencesSensory inputBiologic processesBrainEmotional provocationPatientsPrognosis