2024
Prevalence, Correlates, and Burden of Subthreshold PTSD in US Veterans.
Fischer I, Na P, Harpaz-Rotem I, Marx B, Pietrzak R. Prevalence, Correlates, and Burden of Subthreshold PTSD in US Veterans. The Journal Of Clinical Psychiatry 2024, 85 PMID: 39480145, DOI: 10.4088/jcp.24m15465.Peer-Reviewed Original ResearchConceptsSubthreshold posttraumatic stress disorderPosttraumatic stress disorderPosttraumatic stress disorder symptom clustersLifetime psychiatric disordersUS veteransUS military veteransSymptom-related distressStress disorderPsychiatric disordersSymptom clustersTreating veteransCriterion AMilitary veteransTraumatic eventsCognitive functionWorking case definitionMental healthCriterion FFunctional impairmentVeteransNationally representative sampleFunctional correlatesDisordersElevated oddsGreater oddsLoneliness Trajectories in U.S. Military Veterans: A 3-Year Longitudinal Study of Risk and Protective Factors
Ong A, Cintron D, Rottenberg J, Panaite V, Fischer I, Na P, Jeste D, Pietrzak R. Loneliness Trajectories in U.S. Military Veterans: A 3-Year Longitudinal Study of Risk and Protective Factors. The Journals Of Gerontology Series B 2024, gbae171. PMID: 39390809, DOI: 10.1093/geronb/gbae171.Peer-Reviewed Original ResearchGrowth mixture modelingU.S. military veteransLoneliness trajectoriesMilitary veteransLongitudinal Study of RiskNational Health and ResilienceEarly life adversitySelf-report ratingsProtective factorsWorse cognitive functionMental health concernsPhysical health outcomesHealth concernAdverse childhood experiencesRisk factorsLongitudinal cohort studyStudy of riskNationally representative samplePotential psychosocial riskPromote social connectednessSignificant public health concernVeterans StudyLife adversityThree-step regression analysisCognitive functionHealth correlates of experiential and behavioral avoidance among trauma-exposed veterans
Schwartz E, Palmisano A, Petrakis I, Pietrzak R, Sofuoglu M. Health correlates of experiential and behavioral avoidance among trauma-exposed veterans. Journal Of Psychiatric Research 2024, 176: 213-217. PMID: 38878649, DOI: 10.1016/j.jpsychires.2024.06.014.Peer-Reviewed Original ResearchTrauma-exposed veteransExperiential avoidanceBehavioral avoidanceAnxiety symptomsDepressive symptomsMental health outcomesCognitive dysfunctionPhysical healthPhysical health outcomesHealth outcomesQuality of lifeHealth-related dysfunctionTrauma historyPsychosocial functioningCognitive functionAvoidance behaviorOutcome measuresHealth-related quality of lifeTreatment targetDistressExploratory analysisVeteransHealth-related qualityAvoidanceAnxiety
2017
POSTTRAUMATIC STRESS AND FLUID COGNITION: LONG-TERM OUTCOMES OF THE WORLD TRADE CENTER DISASTER
Clouston S, Pietrzak R, Kotov R, Richards M, Spiro A, Mukherjee S, Luft B, Bromet E. POSTTRAUMATIC STRESS AND FLUID COGNITION: LONG-TERM OUTCOMES OF THE WORLD TRADE CENTER DISASTER. Innovation In Aging 2017, 1: 483-484. PMCID: PMC6246389, DOI: 10.1093/geroni/igx004.1719.Peer-Reviewed Original ResearchPosttraumatic stress disorderStress disorderCognitive functionHead injuryIntrusive stressCurrent posttraumatic stress disorderRe-experiencing symptomsSlower reaction timesWTC Health ProgramLong-term outcomesRisk of dementiaChronic stress disordersWorld Trade Center respondersPoor cognitive functionTraumatic head injuryFluid cognitionCognitive throughputTraumatized individualsCognitive functioningNeuropsychological batteryWorld Trade Center disasterProcessing speedPrevious strokeWTC exposureIncident dementia
2015
Amyloid-β, Anxiety, and Cognitive Decline in Preclinical Alzheimer Disease: A Multicenter, Prospective Cohort Study
Pietrzak RH, Lim YY, Neumeister A, Ames D, Ellis KA, Harrington K, Lautenschlager NT, Restrepo C, Martins RN, Masters CL, Villemagne VL, Rowe CC, Maruff P. Amyloid-β, Anxiety, and Cognitive Decline in Preclinical Alzheimer Disease: A Multicenter, Prospective Cohort Study. JAMA Psychiatry 2015, 72: 284-291. PMID: 25629787, DOI: 10.1001/jamapsychiatry.2014.2476.Peer-Reviewed Original ResearchConceptsPreclinical Alzheimer's diseaseSubjective memory complaintsElevated anxiety symptomsVerbal memoryExecutive functionGlobal cognitionAnxiety symptomsCognitive declineCognitive changesMemory complaintsAβ statusDepressive symptomsLow anxiety groupComprehensive neuropsychological evaluationHigh anxiety groupRole of anxietyFlorbetapir F 18Visual memoryCognitive domainsVisuospatial abilitiesMild cognitive impairmentNeuropsychological evaluationCognitive functionProspective cohort studyMore rapid decline
2014
Reliability and usability of an internet-based computerized cognitive testing battery in community-dwelling older people
Darby D, Fredrickson J, Pietrzak R, Maruff P, Woodward M, Brodtmann A. Reliability and usability of an internet-based computerized cognitive testing battery in community-dwelling older people. Computers In Human Behavior 2014, 30: 199-205. DOI: 10.1016/j.chb.2013.08.009.Peer-Reviewed Original ResearchComputerized test batteryTest batteryComputerized cognitive testing batteryCognitive declineCognitive testing batteryCommunity-dwelling older peopleOlder peopleCommunity-dwelling older adultsSelf-administered testingInternet-based versionTest-retest reliabilityCognitive functionTesting batteryOlder adultsNeurodegenerative conditionsTerms of acceptabilityEarly featureFurther evaluationTest usabilityParticipantsHigh acceptabilityBaseline testMonthly intervalsTechnical difficultiesAcceptability