2024
Stepped Care for Patients to Optimize Whole Recovery (SC-POWR): An Effectiveness Trial Evaluating a Stepped Care Model for Individuals With Opioid Use Disorder and Chronic Pain.
Rossi R, Cutter C, Beitel M, Covelli M, Fiellin D, Kerns R, Vassilieva S, Olabisi D, Barry D. Stepped Care for Patients to Optimize Whole Recovery (SC-POWR): An Effectiveness Trial Evaluating a Stepped Care Model for Individuals With Opioid Use Disorder and Chronic Pain. Substance Use & Addiction Journal 2024, 29767342241245095. PMID: 38606900, PMCID: PMC11470109, DOI: 10.1177/29767342241245095.Peer-Reviewed Original ResearchTreatment-as-usualOpioid use disorderChronic painCognitive behavioral therapyStepped careNonmedical opioid useEffectiveness trialOpioid useAlcohol useSession of exerciseStepped care modelWeekly group sessionsPain-related outcomesStress reductionDecreased pain intensityUse disorderNational Institutes of HealthOpioid use disorder treatmentCare modelInstitutes of HealthAssociated with higher levelsPain intensityPilot study of patientsPain improvementDurability of treatment response
2022
An Analysis of the Role of Mental Health in a Randomized Trial of a Walking Intervention for Black Veterans With Chronic Pain
Hammett PJ, Eliacin J, Makris UE, Allen KD, Kerns RD, Heapy A, Goldsmith ES, Meis LA, Taylor BC, Saenger M, Cross LJS, Do T, Branson M, Burgess DJ. An Analysis of the Role of Mental Health in a Randomized Trial of a Walking Intervention for Black Veterans With Chronic Pain. Journal Of Pain 2022, 24: 55-67. PMID: 36162790, DOI: 10.1016/j.jpain.2022.07.002.Peer-Reviewed Original ResearchConceptsMental health disordersPain-related disabilityCo-occurring mental health disordersUsual careChronic painHealth disordersIntensive treatmentBlack veteransVA health care systemChronic musculoskeletal painChronic pain patientsMental health diagnosesTelephone coaching sessionsHealth care systemMusculoskeletal painPain patientsBlack patientsPainSecondary analysisPatientsMental healthCare systemHealth diagnosisIntervention effectivenessDisordersBrief Educational Video plus Telecare to Enhance Recovery for Older Emergency Department Patients with Acute Musculoskeletal Pain: an update to the study protocol for a randomized controlled trial
Hurka-Richardson K, Platts-Mills TF, McLean SA, Weinberger M, Stearns SC, Bush M, Quackenbush E, Chari S, Aylward A, Kroenke K, Kerns RD, Weaver MA, Keefe FJ, Berkoff D, Meyer ML. Brief Educational Video plus Telecare to Enhance Recovery for Older Emergency Department Patients with Acute Musculoskeletal Pain: an update to the study protocol for a randomized controlled trial. Trials 2022, 23: 400. PMID: 35550175, PMCID: PMC9096747, DOI: 10.1186/s13063-022-06310-z.Peer-Reviewed Original ResearchConceptsUrgent care clinicMusculoskeletal painCare clinicsOlder emergency department (ED) patientsAcute care visitsAcute musculoskeletal painEmergency department patientsWeeks of enrollmentCOVID-19 pandemicBrief educational videoCare visitsOpioid useDepartment patientsChronic painEmergency departmentStudy protocolFavorable outcomeInclusion criteriaRecruitment sitesEligibility criteriaMedical treatmentBETTER trialRemote recruitmentPainParticipant enrollmentTaking ACTION to Reduce Pain: a Randomized Clinical Trial of a Walking-Focused, Proactive Coaching Intervention for Black Patients with Chronic Musculoskeletal Pain
Burgess DJ, Hagel Campbell E, Hammett P, Allen KD, Fu SS, Heapy A, Kerns RD, Krein SL, Meis LA, Bangerter A, Cross LJS, Do T, Saenger M, Taylor BC. Taking ACTION to Reduce Pain: a Randomized Clinical Trial of a Walking-Focused, Proactive Coaching Intervention for Black Patients with Chronic Musculoskeletal Pain. Journal Of General Internal Medicine 2022, 37: 3585-3593. PMID: 35132545, PMCID: PMC9585120, DOI: 10.1007/s11606-021-07376-2.Peer-Reviewed Original ResearchConceptsBlack patientsUsual careSecondary outcomesPain intensityPrimary outcomeChronic painIntervention participantsVA health care systemMasked outcome assessmentChronic musculoskeletal painMental health comorbiditiesChronic pain outcomesAverage daily stepsTelephone coaching sessionsMain MeasuresPrimary outcomesCoaching interventionHealth care systemResultsThe interventionHealth comorbiditiesMusculoskeletal painPain outcomesSevere chronicPain interferenceGlobal ImpressionMeasuresPrimary outcomesArtificial Intelligence (AI) to improve chronic pain care: Evidence of AI learning
Piette J, Newman S, Krein S, Marinec N, Chen J, Williams D, Edmond S, Driscoll M, LaChappelle K, Maly M, Kim H, Farris K, Higgins D, Kerns R, Heapy A. Artificial Intelligence (AI) to improve chronic pain care: Evidence of AI learning. Intelligence-Based Medicine 2022, 6: 100064. DOI: 10.1016/j.ibmed.2022.100064.Peer-Reviewed Original ResearchPatient interactionsPatient subgroupsInteractive voice response callsPain-related interferenceComparative effectiveness trialChronic pain careCourse of therapyPedometer step countsDisease management programsCognitive behavioral therapyCBT-CPChronic painMore patientsPain careTreatment modalitiesTreatment recommendationsEffectiveness trialPatientsStep countBehavioral therapyClinician timeWeeksTherapy sessionsMethods DataTherapist feedback
2021
Optimizing the Impact of Pragmatic Clinical Trials for Veteran and Military Populations: Lessons From the Pain Management Collaboratory
Ali J, Antonelli M, Bastian L, Becker W, Brandt CA, Burgess DJ, Burns A, Cohen SP, Davis AF, Dearth CL, Dziura J, Edwards R, Erdos J, Farrokhi S, Fritz J, Geda M, George SZ, Goertz C, Goodie J, Hastings SN, Heapy A, Ilfeld BM, Katsovich L, Kerns RD, Kyriakides TC, Lee A, Long CR, Luther SL, Martino S, Matheny ME, McGeary D, Midboe A, Pasquina P, Peduzzi P, Raffanello M, Rhon D, Rosen M, Esposito ER, Scarton D, Hastings SN, Seal K, Silliker N, Taylor S, Taylor SL, Tsui M, Wright FS, Zeliadt S. Optimizing the Impact of Pragmatic Clinical Trials for Veteran and Military Populations: Lessons From the Pain Management Collaboratory. Military Medicine 2021, 187: 179-185. PMID: 34791412, PMCID: PMC9389906, DOI: 10.1093/milmed/usab458.Peer-Reviewed Original ResearchConceptsPragmatic clinical trialsPain Management CollaboratoryClinical trialsMultisite pragmatic clinical trialManagement of painDual public health crisesCommon co-occurring conditionsPragmatic trial designUnmet healthcare needsMilitary Health SystemCo-occurring conditionsPublic health crisisPain managementChronic painNonpharmacological approachesOpioid misuseMultifactorial etiologyTrial designVeterans AffairsMilitary populationHealthcare needsHealth systemNational InstitutePainCOVID-19 pandemicPsychological Interventions for the Treatment of Chronic Pain in Adults
Driscoll MA, Edwards RR, Becker WC, Kaptchuk TJ, Kerns RD. Psychological Interventions for the Treatment of Chronic Pain in Adults. Psychological Science In The Public Interest 2021, 22: 52-95. PMID: 34541967, DOI: 10.1177/15291006211008157.Peer-Reviewed Original ResearchConceptsPsychological interventionsCognitive behavioral therapyChronic painPrimary conceptual frameworkPsychological processesCo-occurring disordersIndividual differencesPsychological treatmentPsychological approachResilience factorsCommitment TherapyExpression therapyBiopsychosocial modelAdditional scientific knowledgeComplex experienceImpact of painMultiple pain conditionsSerious public health concernModel of carePublic health concernInterventionOpioid therapyAdultsPain conditionsMindfulnessPain and smoking study (PASS): A comparative effectiveness trial of smoking cessation counseling for veterans with chronic pain
Bastian LA, Driscoll M, DeRycke E, Edmond S, Mattocks K, Goulet J, Kerns RD, Lawless M, Quon C, Selander K, Snow J, Casares J, Lee M, Brandt C, Ditre J, Becker W. Pain and smoking study (PASS): A comparative effectiveness trial of smoking cessation counseling for veterans with chronic pain. Contemporary Clinical Trials Communications 2021, 23: 100839. PMID: 34485755, PMCID: PMC8391053, DOI: 10.1016/j.conctc.2021.100839.Peer-Reviewed Original ResearchCognitive-behavioral interventionsBehavioral interventionsAdaptive coping strategiesPain-related anxietyChronic painSmoking studiesGreater pain intensityCoping strategiesMotivational interviewingSmoking cessationPain-related functional interferenceTelephone counseling interventionCounseling interventionNicotine replacement therapyMental health comorbiditiesComparative effectiveness trialRandomized clinical trialsParticipantsEffectiveness trialRelapse managementVeteransCessation counselingBaseline characteristicsHealth comorbiditiesMedian ageSociodemographic and clinical correlates of gabapentin receipt with and without opioids among a national cohort of patients with HIV
Oldfield BJ, Li Y, Vickers-Smith R, Becker WC, Barry DT, Crystal S, Gordon KS, Kerns RD, Rentsch CT, Marshall BDL, Edelman EJ. Sociodemographic and clinical correlates of gabapentin receipt with and without opioids among a national cohort of patients with HIV. AIDS Care 2021, 34: 1053-1063. PMID: 34114904, PMCID: PMC8664891, DOI: 10.1080/09540121.2021.1939851.Peer-Reviewed Original ResearchConceptsOpioid useHigh dosesSelf-reported opioid useVeterans Aging Cohort StudyHigh-dose opioidsMean daily doseAging Cohort StudyHigh-dose benzodiazepinesNational prospective cohortOpioid doseOpioid receiptCohort studyFoot painProspective cohortDaily doseIndependent predictorsChronic painPain interferenceClinical variablesClinical correlatesNational cohortMultinomial logistic regressionPWHLogistic regressionOpioidsCorrelates of Manual Therapy and Acupuncture Use Among Rural Patients Seeking Conventional Pain Management: A Cross-sectional Study
Feinberg TM, Coleman B, Innes KE, Kerns RD, Jackson B, Lisi A, Majoris N, Brandt C. Correlates of Manual Therapy and Acupuncture Use Among Rural Patients Seeking Conventional Pain Management: A Cross-sectional Study. Journal Of Manipulative And Physiological Therapeutics 2021, 44: 330-343. PMID: 33896602, DOI: 10.1016/j.jmpt.2021.01.002.Peer-Reviewed Original ResearchConceptsComplementary health approachesManual therapyCross-sectional studyPain managementAcupuncture useHealth approachAge-adjusted logistic regressionConventional pain managementCurrent chronic painHigh pain burdenPrior opioid usePain scale scoresMind-body therapiesHealth-related factorsPain-related distressPain burdenOpioid useRheumatology clinicChronic painClinical outcomesPain carePain distressRural patientsMajority of participantsPrescription medicationsDevelopment and Implementation of the Military Treatment Facility Engagement Committee (MTFEC) to Support Pragmatic Clinical Trials in the Military Health System
Scarton DV, Roddy WT, Taylor JA, Geda M, Brandt CA, Peduzzi P, Kerns RD, Pasquina PF. Development and Implementation of the Military Treatment Facility Engagement Committee (MTFEC) to Support Pragmatic Clinical Trials in the Military Health System. Military Medicine 2021, 186: 70-75. PMID: 33499543, PMCID: PMC7980475, DOI: 10.1093/milmed/usaa368.Peer-Reviewed Original ResearchConceptsPain Management CollaboratoryPragmatic clinical trialsMilitary treatment facilitiesHealth care systemPain managementClinical trialsDOD health care systemVA health care systemCare systemChronic pain managementService membersTraumatic brain injuryMilitary Health SystemMilitary service membersChronic painNonpharmacological approachesBrain injuryLimb lossClinical practiceHealth systemCoordinating CenterTrialsVA programsNational InstituteDepartment of DefensePain, Complex Chronic Conditions and Potential Inappropriate Medication in People with Dementia. Lessons Learnt for Pain Treatment Plans Utilizing Data from the Veteran Health Administration
Husebo BS, Kerns RD, Han L, Skanderson M, Gnjidic D, Allore HG. Pain, Complex Chronic Conditions and Potential Inappropriate Medication in People with Dementia. Lessons Learnt for Pain Treatment Plans Utilizing Data from the Veteran Health Administration. Brain Sciences 2021, 11: 86. PMID: 33440668, PMCID: PMC7827274, DOI: 10.3390/brainsci11010086.Peer-Reviewed Original ResearchChronic complex conditionsSevere pain intensityVeterans Health AdministrationPain intensityHealth AdministrationDiscontinuation of opioidsInappropriate pain managementPain treatment planPotential inappropriate medicationsInappropriate medication useComplex chronic conditionsNon-pharmacological approachesImportant risk factorAdverse drug reactionsFinal analytic sampleAnalgesic efficacyInappropriate medicationsOpioid medicationsPain medicationMedication usePain managementPersistent painChronic painMedical illnessOutpatient visitsIncorporating walking into cognitive behavioral therapy for chronic pain: safety and effectiveness of a personalized walking intervention
Heapy AA, Tankha H, Higgins DM, Driscoll M, LaChappelle KM, Goulet JL, Buta E, Piette JD, Kerns RD, Krein SL. Incorporating walking into cognitive behavioral therapy for chronic pain: safety and effectiveness of a personalized walking intervention. Journal Of Behavioral Medicine 2021, 44: 260-269. PMID: 33386530, DOI: 10.1007/s10865-020-00193-8.Peer-Reviewed Original ResearchConceptsAdverse eventsCognitive behavioral therapyChronic painBehavioral therapyCBT-CPLongstanding painWalking interventionsDaily stepsTreatment groupsPainInteractive voice responseStudy sampleWeekly goalsSignificant differencesSignificant increaseTherapyTreatmentParticipantsVoice responseSafetyPersonsBaselineWeeks
2020
Pivoting to virtual delivery for managing chronic pain with nonpharmacological treatments: implications for pragmatic research
Fritz JM, Davis AF, Burgess DJ, Coleman B, Cook C, Farrokhi S, Goertz C, Heapy A, Lisi AJ, McGeary DD, Rhon DI, Taylor SL, Zeliadt S, Kerns RD. Pivoting to virtual delivery for managing chronic pain with nonpharmacological treatments: implications for pragmatic research. Pain 2020, 162: 1591-1596. PMID: 33156148, PMCID: PMC8089114, DOI: 10.1097/j.pain.0000000000002139.Peer-Reviewed Original ResearchPredictors of engagement in an internet-based cognitive behavioral therapy program for veterans with chronic low back pain
Solar C, Halat AM, MacLean RR, Rajeevan H, Williams DA, Krein SL, Heapy AA, Bair MJ, Kerns RD, Higgins DM. Predictors of engagement in an internet-based cognitive behavioral therapy program for veterans with chronic low back pain. Translational Behavioral Medicine 2020, 11: 1274-1282. PMID: 33098304, DOI: 10.1093/tbm/ibaa098.Peer-Reviewed Original ResearchConceptsChronic low back painLow back painClinical characteristicsBack painChronic painEASE programParticipant characteristicsInternet-based cognitive behavioural therapy programmeInternet-based cognitive behavioral therapy interventionInternet-based interventionsCognitive behavioral therapy interventionInternet-based programCognitive behavioral therapy programBehavioral therapy interventionBehavioral therapy programRace/ethnicityPain careMean ageNumber of loginsIncreased ageTherapy interventionWeek trialPainTherapy programPredictors of engagementIdentifying Multisite Chronic Pain with Electronic Health Records Data
Von Korff M, DeBar LL, Deyo RA, Mayhew M, Kerns RD, Goulet JL, Brandt C. Identifying Multisite Chronic Pain with Electronic Health Records Data. Pain Medicine 2020, 21: 3387-3392. PMID: 32918481, PMCID: PMC7770230, DOI: 10.1093/pm/pnaa295.Peer-Reviewed Original ResearchConceptsMultisite chronic painElectronic health care dataChronic painChronic pain impactElectronic health recordsHealth care dataCare dataPain impactHealth recordsLong-term opioid useCommon chronic pain conditionsPain-related disabilityChronic pain conditionsKaiser Permanente NorthwestElectronic health record dataHealth record dataPositive predictive valueOpioid usePain severityPain conditionsDepressive symptomsPainPredictive valueEpidemiological researchRecord dataAdapting to disruption of research during the COVID-19 pandemic while testing nonpharmacological approaches to pain management
Coleman BC, Kean J, Brandt CA, Peduzzi P, Kerns RD, . Adapting to disruption of research during the COVID-19 pandemic while testing nonpharmacological approaches to pain management. Translational Behavioral Medicine 2020, 10: 827-834. PMID: 32885815, PMCID: PMC7499692, DOI: 10.1093/tbm/ibaa074.Peer-Reviewed Original ResearchMeSH KeywordsBetacoronavirusChronic PainCommunicable Disease ControlCoronavirus InfectionsCOVID-19HumansMental HealthNational Institutes of Health (U.S.)Pain ManagementPandemicsPatient SelectionPneumonia, ViralResearchSARS-CoV-2Socioeconomic FactorsUnited StatesUnited States Department of Veterans AffairsConceptsPain Management CollaboratoryPragmatic clinical trialsChronic painCOVID-19 pandemicUrgent public health challengePain management interventionsClinical care teamPatient-reported measuresPublic health challengeVeterans Health SystemCOVID-19Pain managementNonpharmacological approachesStudy protocolClinical trialsCare teamIntervention deliveryHealth departmentsHealth outcomesHealth challengesHealth systemStudy designMental healthDisruption of researchParticipant recruitmentBrief educational video plus telecare to enhance recovery for older emergency department patients with acute musculoskeletal pain: study protocol for the BETTER randomized controlled trial
Platts-Mills TF, McLean SA, Weinberger M, Stearns SC, Bush M, Teresi BB, Hurka-Richardson K, Kroenke K, Kerns RD, Weaver MA, Keefe FJ. Brief educational video plus telecare to enhance recovery for older emergency department patients with acute musculoskeletal pain: study protocol for the BETTER randomized controlled trial. Trials 2020, 21: 615. PMID: 32631400, PMCID: PMC7336469, DOI: 10.1186/s13063-020-04552-3.Peer-Reviewed Original ResearchConceptsChronic musculoskeletal painMusculoskeletal painEmergency departmentUsual careOpioid useChronic painOlder adultsAnalgesic-related side effectsLong-term opioid useOlder emergency department (ED) patientsAcute musculoskeletal painEmergency department patientsCause of disabilityPublic health priorityBrief educational videoDiscussionThis trialPain severitySecondary outcomesSixty patientsDepartment patientsPrimary outcomeHealthcare utilizationStudy enrollmentPhysical functionStudy protocolTreatment of a Large Cohort of Veterans Experiencing Musculoskeletal Disorders with Spinal Cord Stimulation in the Veterans Health Administration: Veteran Characteristics and Outcomes
Wandner LD, Fenton BT, Goulet JL, Carroll CM, Heapy A, Higgins DM, Bair MJ, Sandbrink F, Kerns RD. Treatment of a Large Cohort of Veterans Experiencing Musculoskeletal Disorders with Spinal Cord Stimulation in the Veterans Health Administration: Veteran Characteristics and Outcomes. Journal Of Pain Research 2020, 13: 1687-1697. PMID: 32753944, PMCID: PMC7354010, DOI: 10.2147/jpr.s241567.Peer-Reviewed Original ResearchMusculoskeletal disordersSCS implantsOpioid therapyPain scoresVeterans Health Administration facilitiesSpinal cord stimulator implantationOutcomes of veteransPainful musculoskeletal disordersSpinal cord stimulationVeterans Health AdministrationDepressive disorder diagnosisEvidence of benefitSubstance use disordersPercent of veteransSignificant overall decreaseMSD cohortOpioid doseBMI 25Medical comorbiditiesStimulator implantationChronic painCord stimulationInclusion diagnosisVeteran characteristicsLarge cohort
2019
Pain-related illness intrusiveness is associated with lower activity engagement among persons with multiple sclerosis
Gromisch ES, Kerns RD, Beauvais J. Pain-related illness intrusiveness is associated with lower activity engagement among persons with multiple sclerosis. Multiple Sclerosis And Related Disorders 2019, 38: 101882. PMID: 31812040, DOI: 10.1016/j.msard.2019.101882.Peer-Reviewed Original ResearchConceptsWest Haven-Yale Multidimensional Pain InventoryIllness Intrusiveness Ratings ScaleIllness intrusivenessMultiple sclerosisPain experienceActivity engagementNorth American Research CommitteeLeast mild painMultidimensional Pain InventoryLower activity engagementDepression symptom severityMild painPain InventoryChronic painExploratory mediation analysisPainSymptom severityDaily functioningRating ScalePositive coping strategiesSignificant predictorsSclerosisResearch CommitteeMediation analysisCovariates