A membrane-associated inhibitory axis of MHC-I presentation for cancer immune evasion
Lu Q, Chen X, Zhou H, Liu J, Nadorp B, Lasry A, Sun Z, Zhang J, Cammer M, Wang K, Ciantra Z, You J, Guo Q, Zhang H, Sengupta D, Boukhris A, Liu C, Cresswell P, Dahia P, Aifantis I, Wang J. A membrane-associated inhibitory axis of MHC-I presentation for cancer immune evasion. The Journal Of Immunology 2023, 210: 89.12-89.12. DOI: 10.4049/jimmunol.210.supp.89.12.Peer-Reviewed Original ResearchAcute myeloid leukemiaInhibitory axisSolid cancersImmune evasionT cell-dependent mannerCancer immune evasionImmune checkpoint blockadeT cell immunityNumber of tumorsMultiple solid cancersCell-dependent mannerApplicable therapeutic targetMDS FoundationCancer survivalMyeloid leukemiaTherapeutic targetTransmembrane protein 127Tumor growthGene signatureCancer treatmentMHCPeptide-MHCLeukemiaSushi domainCancer