2017
Bioengineered lungs generated from human iPSCs‐derived epithelial cells on native extracellular matrix
Ghaedi M, Le AV, Hatachi G, Beloiartsev A, Rocco K, Sivarapatna A, Mendez JJ, Baevova P, Dyal RN, Leiby KL, White ES, Niklason LE. Bioengineered lungs generated from human iPSCs‐derived epithelial cells on native extracellular matrix. Journal Of Tissue Engineering And Regenerative Medicine 2017, 12: e1623-e1635. PMID: 29024475, PMCID: PMC5991621, DOI: 10.1002/term.2589.Peer-Reviewed Original ResearchConceptsEpithelial progenitor cellsProgenitor cellsStem cellsEpithelial cellsLung progenitor cellsLung epithelial cellsHuman lungHuman-derived cellsReliable cell sourceNative extracellular matrixEarly stepsExtracellular matrixRat lungImportant early stepHuman iPSCLung regenerationLung tissue regenerationHuman lung tissueIPSCsLung scaffoldsCell sourceCellsEpithelial markersLung transplantationTissue regeneration
2004
The Plasmodium falciparum Vps4 homolog mediates multivesicular body formation
Yang M, Coppens I, Wormsley S, Baevova P, Hoppe H, Joiner K. The Plasmodium falciparum Vps4 homolog mediates multivesicular body formation. Journal Of Cell Science 2004, 117: 3831-3838. PMID: 15252121, DOI: 10.1242/jcs.01237.Peer-Reviewed Original ResearchMeSH KeywordsAdenosine TriphosphatasesAdenosine TriphosphateAnimalsCell ProliferationCholesterolCloning, MolecularCOS CellsCytoplasmCytosolDNAElectroporationEndosomal Sorting Complexes Required for TransportEndosomesFibroblastsGreen Fluorescent ProteinsHumansHydrolysisImmunoblottingLipoproteins, LDLMicroscopy, ElectronMutationPhylogenyPlasmodium falciparumProtein Structure, TertiaryProtozoan ProteinsSubcellular FractionsToxoplasmaTransfectionTransgenesConceptsMultivesicular bodiesCOS cellsRelated parasite Toxoplasma gondiiUnique secretory organellesClass E genesMultivesicular body formationEndosomal multivesicular bodiesHost cell invasionLarge vesicular structuresPlasmodium falciparum homologP. falciparumVps4 functionEndosomal intermediatesApicomplexan familyPhylogenetic boundariesATP bindingSecretory organellesEarly endosomesParasite Toxoplasma gondiiP. falciparum trophozoitesATP hydrolysisInternal membranesT. gondiiBody formationCell invasion