2021
Placenta-derived interferon-stimulated gene 20 controls ZIKA virus infection
Ding J, Aldo P, Roberts CM, Stabach P, Liu H, You Y, Qiu X, Jeong J, Maxwell A, Lindenbach B, Braddock D, Liao A, Mor G. Placenta-derived interferon-stimulated gene 20 controls ZIKA virus infection. EMBO Reports 2021, 22: embr202152450. PMID: 34405956, PMCID: PMC8490983, DOI: 10.15252/embr.202152450.Peer-Reviewed Original ResearchConceptsZika virus infectionVirus infectionTrophoblast cellsPotential immune modulatory functionsInterferon-stimulated gene 20Anti-viral treatmentHigh-risk populationImmune modulatory functionsAnti-viral responseZika viral infectionImportance of preventionPregnant womenReplacement therapyViral infectionFetal developmentZika virusViral titersModulatory functionViral replicationInfectionAdverse effectsGene 20PregnancyPlacentaRNA viruses
2010
Placental Viral Infection Sensitizes to Endotoxin‐Induced Pre‐Term Labor: A Double Hit Hypothesis
Cardenas I, Mor G, Aldo P, Lang SM, Stabach P, Sharp A, Romero R, Mazaki‐Tovi S, Gervasi M, Means RE. Placental Viral Infection Sensitizes to Endotoxin‐Induced Pre‐Term Labor: A Double Hit Hypothesis. American Journal Of Reproductive Immunology 2010, 65: 110-117. PMID: 20712808, PMCID: PMC3025809, DOI: 10.1111/j.1600-0897.2010.00908.x.Peer-Reviewed Original ResearchConceptsPre-term labourPre-term deliveryDouble-hit hypothesisViral infectionPregnancy outcomesBacterial infectionsCytokine/chemokine profilesHit hypothesisConcurrent bacterial infectionFetal immune responsePro-inflammatory cytokinesWild-type miceHuman primary trophoblastsMurine gammaherpesvirus 68Fetal deathChemokine profilesPoor prognosisPregnant womenAdverse outcomesPregnant miceLPS treatmentImmune responseBacterial productsPrimary trophoblastsLow doses
1996
Identification of a small cytoplasmic ankyrin (AnkG119) in the kidney and muscle that binds beta I sigma spectrin and associates with the Golgi apparatus.
Devarajan P, Stabach PR, Mann AS, Ardito T, Kashgarian M, Morrow JS. Identification of a small cytoplasmic ankyrin (AnkG119) in the kidney and muscle that binds beta I sigma spectrin and associates with the Golgi apparatus. Journal Of Cell Biology 1996, 133: 819-830. PMID: 8666667, PMCID: PMC2120834, DOI: 10.1083/jcb.133.4.819.Peer-Reviewed Original ResearchConceptsMDCK cell lysatesGolgi apparatusMDCK cellsBeta IDomain IPlasma membrane localizationTrans-Golgi networkPutative regulatory domainCell lysatesPolarized vesicle transportMembrane-associated proteinsCell cycle controlSubset of endosomesNovel ankyrinPolarity developmentVesicle transportMotif characteristicMembrane localizationRegulatory domainProtein microdomainsSequence comparisonAlternative transcriptsRepetitive domainSubconfluent MDCK cellsMembrane skeleton