Featured Publications
Access challenges to opioid use disorder treatment among individuals experiencing homelessness: Voices from the streets
Hsu M, Jung O, Kwan L, Jegede O, Martin B, Malhotra A, Suzuki J. Access challenges to opioid use disorder treatment among individuals experiencing homelessness: Voices from the streets. Journal Of Substance Use And Addiction Treatment 2023, 157: 209216. PMID: 37981243, DOI: 10.1016/j.josat.2023.209216.Peer-Reviewed Original ResearchOpioid use disorderSocioeconomic statusUse disordersCOVID-19 pandemicBuprenorphine/naloxoneActive substance useUse disorder treatmentPercent of participantsActive prescriptionMOUD accessSublingual buprenorphineOUD treatmentTreatment gapTreatment accessMOUDDisorder treatmentBuprenorphineAdverse effectsSubstance useVulnerable populationsIndividual-level factorsMedicationsAccess challengesWhite participantsDisordersCorrelates of Perceived Discrimination Related to Substance Use Disorders Among Patients in Methadone Maintenance Treatment
Nwanaji-Enwerem U, Beitel M, Oberleitner D, Gazzola M, Eggert K, Oberleitner L, Jegede O, Zheng X, Redeker N, Madden L, Barry D. Correlates of Perceived Discrimination Related to Substance Use Disorders Among Patients in Methadone Maintenance Treatment. Journal Of Psychoactive Drugs 2023, 56: 530-540. PMID: 37399330, PMCID: PMC10761588, DOI: 10.1080/02791072.2023.2230571.Peer-Reviewed Original ResearchMethadone maintenance treatmentSubstance use disordersLogistic regression modelsUse disordersMaintenance treatmentTreatment-related characteristicsOpioid use disorderFinal logistic regression modelBSI-18 depressionAge of onsetRegression modelsMMT programDepressive symptomsMeasures of demographicsPatientsBivariate analysisSubstance abuseSignificant correlatesDisordersCorrelatesMedian splitAgeParticipantsTreatmentLikert-type scaleThe Current Status of Medical Student Education on Opioids
Jegede O, Na P, Petrakis I, Muvvala S. The Current Status of Medical Student Education on Opioids. 2023, 121-138. DOI: 10.1093/oxfordhb/9780197618431.013.5.Peer-Reviewed Original ResearchThe Impact of High-Potency Synthetic Opioids on Pharmacotherapies for Opioid Use Disorder: A Scoping Review
Jegede O, De Aquino J, Hsaio C, Caldwell E, Funaro M, Petrakis I, Muvvala S. The Impact of High-Potency Synthetic Opioids on Pharmacotherapies for Opioid Use Disorder: A Scoping Review. Journal Of Addiction Medicine 2024, 18: 499-510. PMID: 39356620, PMCID: PMC11449257, DOI: 10.1097/adm.0000000000001356.Peer-Reviewed Original ResearchNonmedical opioid useOpioid use disorderOpioid useWithdrawal symptomsTreatment outcomesSymptoms prior to treatmentUse disorderRisk of precipitated withdrawalLow-dose buprenorphineSynthetic opioidsPotency synthetic opioidsConclusions Current evidencePrecipitated withdrawalRisk of overdoseDosing strategiesPharmacological interactionsClinical significanceDecreased riskWeb of ScienceOpioidInclusion criteriaCurrent evidenceClinical implicationsMOUDPain
2024
Addressing Racial and Ethnic Inequities in Opioid Overdose Mortality: Strategies for Equitable Interventions and Structural Change
Cruz F, Jegede O. Addressing Racial and Ethnic Inequities in Opioid Overdose Mortality: Strategies for Equitable Interventions and Structural Change. Current Psychiatry Reports 2024, 1-7. PMID: 39496984, DOI: 10.1007/s11920-024-01556-7.Peer-Reviewed Original ResearchOpioid overdose mortalityOverdose mortalityAdaptation of evidence-based interventionsSocial determinants of healthCultural adaptation of evidence-based interventionsEthnic inequalitiesDeterminants of healthEvidence-based interventionsHarm reduction servicesSubstance use disorder preventionSocial determinantsTailored interventionsEquitable interventionsEquity-based frameworkOpioid use disorderReduction servicesSubstance use outcomesAnti-racism praxisCultural adaptationStructural competencyStructural racismDisorder preventionPolicy-levelInterventionUse disorderAssociations Among Sleep, Pain, and Medications for Opioid Use Disorder: a Scoping Review
Hsaio C, DiMeola K, Jegede O, Funaro M, Langstengel J, Yaggi H, Barry D. Associations Among Sleep, Pain, and Medications for Opioid Use Disorder: a Scoping Review. Current Addiction Reports 2024, 1-17. DOI: 10.1007/s40429-024-00606-7.Peer-Reviewed Original ResearchOpioid use disorderOUD severityUse disorderTreatment characteristicsOpioid use disorder treatment settingsTreatment of sleepDosing scheduleDisorder severityOpioidPainWeb of ScienceAssessed patientsCochrane LibraryMeasures of sleepMOUD treatmentCurrent evidenceMOUDSleepSleep disturbanceProvider preferencesPatientsStudy examined sleepDisordersTreatment settingsMedicationDisentangling the effects of racism-related stress on opioid use disorder and chronic pain outcomes
Nunes J, Jegede O, De Aquino J. Disentangling the effects of racism-related stress on opioid use disorder and chronic pain outcomes. The American Journal Of Drug And Alcohol Abuse 2024, 50: 455-461. PMID: 39018662, DOI: 10.1080/00952990.2024.2369866.Peer-Reviewed Original ResearchOpioid use disorderUse disorderRacism-related stressChronic pain outcomesOpioid overdose mortality ratesOverdose mortality ratesHealthcare disparitiesBiopsychosocial burdenPain outcomesPrescribed opioidsUndertreated painChronic painPain managementOpioid mortalityPerpetuate stigmaTreat painPain experienceOpioidPainRisk factorsMinoritized populationsMinoritized peopleMortality rateDisparitiesAddiction treatment
2023
Opioid use disorder amongst young people living with HIV: A 10-year trend
Ikekwere J, Eiger R, Heward B, Longcoy J, Okobi O, Oladunjoye A, Onyeaka H, Kompella S, Jegede O. Opioid use disorder amongst young people living with HIV: A 10-year trend. Psychiatry Research Communications 2023, 3: 100140. DOI: 10.1016/j.psycom.2023.100140.Peer-Reviewed Original ResearchOpioid use disorderMental health diagnosesUse disordersDiagnosis of OUDRisk of OUDNational Inpatient Sample dataMajor public health concernNew HIV diagnosesMultivariable logistic regressionMental health servicesHIV-positive young peoplePublic health concernMental health issuesComorbid HIVHIV diagnosisOpioid useOUD diagnosisEffective treatmentHigh riskHIVPrevention strategiesICD codesTargeted preventionDrug useHealth services
2022
What’s in a Name? Terminology Preferences Among Patients Receiving Methadone Treatment
Gazzola MG, Maclean E, Beitel M, Carmichael ID, Cammack KM, Eggert KF, Roehrich T, Madden LM, Jegede O, Zheng X, Bergman E, Barry DT. What’s in a Name? Terminology Preferences Among Patients Receiving Methadone Treatment. Journal Of General Internal Medicine 2022, 38: 653-660. PMID: 36163526, PMCID: PMC9971370, DOI: 10.1007/s11606-022-07813-w.Peer-Reviewed Original ResearchConceptsOpioid use disorderSubstance use disordersMethadone treatmentUse disordersOutpatient methadone treatment programMethadone treatment programsPresenting problemPreferences of patientsTerminology preferencesSubstance-dependent personsCross-sectional surveyAdult patientsMean ageUnivariate analysisMain MeasuresParticipantsPatientsTreatment programKey ResultsWeSubstance abuseSubstance useDisordersSignificant differencesTreatmentDemographic differencesAddiction counselorsCommunity based buprenorphine micro-induction in the context of methadone maintenance treatment and fentanyl – Case report
Kaliamurthy S, Jegede O, Hermes G. Community based buprenorphine micro-induction in the context of methadone maintenance treatment and fentanyl – Case report. Journal Of Addictive Diseases 2022, 41: 175-180. PMID: 35377273, DOI: 10.1080/10550887.2022.2051985.Peer-Reviewed Case Reports and Technical NotesConceptsFull opioid agonistsOpioid use disorderFentanyl useOpioid agonistsUse disordersMethadone doseCommunity-based methadone maintenance programIllicit fentanyl useCharacteristics of patientsMethadone maintenance treatmentMethadone maintenance programMaintenance treatmentOutpatient clinicTime of inductionOutpatient settingCommunity clinicsBuprenorphinePatientsMore cliniciansAgonistsDisordersClinicCliniciansDoseWithdrawal
2021
Posterior Reversible Encephalopathy Syndrome (PRES) in a Patient with Opioid Use Disorder
Tumenta T, Adeyemo S, Oladeji O, Jegede O, Laurent B, Olupona T. Posterior Reversible Encephalopathy Syndrome (PRES) in a Patient with Opioid Use Disorder. Case Reports In Psychiatry 2021, 2021: 9999481. PMID: 34221530, PMCID: PMC8225411, DOI: 10.1155/2021/9999481.Peer-Reviewed Original ResearchPosterior reversible encephalopathy syndromeReversible encephalopathy syndromeHeroin use disorderEncephalopathy syndromeUse disordersSignificant white matter diseaseClinical-radiographic syndromeOpioid use disorderCerebral white matterWhite matter diseaseOpioid withdrawalNeurology teamEndothelial injuryMyelin damageCerebral autoregulationClinical symptomsCT headMedical floorChronic headacheMental statusRisk factorsRadiographic syndromeMultifactorial etiologyCerebral hemispheresWhite matter