2023
Posttransplant Tertiary Lymphoid Organs
Ruddle N. Posttransplant Tertiary Lymphoid Organs. Transplantation 2023, 108: 1090-1099. PMID: 37917987, PMCID: PMC11042531, DOI: 10.1097/tp.0000000000004812.Peer-Reviewed Original ResearchTertiary lymphoid organsOrgan rejectionLymphoid organsCase of immunosuppressionEctopic lymphoid structuresDevelopment of lymphomaLymphoid neogenesisLymph nodesIschemic reperfusionChronic inflammationLymphoid structuresNephrotoxic agentsTumor antigensVascular componentLymphoid cellsTherapeutic manipulationSustained exposureMicrobial infectionsCellular compositionStaging schemeCancerOrgansRejectionImmunosuppressionReperfusion
2016
High Endothelial Venules and Lymphatic Vessels in Tertiary Lymphoid Organs: Characteristics, Functions, and Regulation
Ruddle NH. High Endothelial Venules and Lymphatic Vessels in Tertiary Lymphoid Organs: Characteristics, Functions, and Regulation. Frontiers In Immunology 2016, 7: 491. PMID: 27881983, PMCID: PMC5101196, DOI: 10.3389/fimmu.2016.00491.Peer-Reviewed Original ResearchTertiary lymphoid organsHigh endothelial venulesSecondary lymphoid organsLymph nodesAntigen-presenting cellsLymphoid organsEndothelial venulesLymphatic vesselsStromal cellsCentral memory cellsPrimary lymphoid organsTransport antigensGraft rejectionEffector cellsChemokine expressionChronic inflammationPeyer's patchesAntigen presentationInflammatory signalsB cellsBone marrowImmune systemReticular cellsMicrobial infectionsCellular compositionTertiary Lymphoid Tissues
Ruddle N. Tertiary Lymphoid Tissues. 2016, 480-485. DOI: 10.1016/b978-0-12-374279-7.07012-0.Peer-Reviewed Original ResearchTertiary lymphoid organsTertiary lymphoid tissueSecondary lymphoid organsLymphoid organsLymphoid tissueConventional lymphoid organsChronic graft rejectionHigh endothelial venulesChronic microbial infectionsStromal cellular compositionAntigen primingNonlymphoid organsGraft rejectionDeterminant spreadingLymph nodesChronic inflammationEndothelial venulesClinical diseaseImmune responseInfectious organismsMicrobial infectionsCellular compositionLymphatic vesselsEctopic sitesAutoimmunity