Featured Publications
Application of multiplex amplicon deep-sequencing (MAD-seq) to screen for putative drug resistance markers in the Necator americanus isotype-1 β-tubulin gene
George S, Suwondo P, Akorli J, Otchere J, Harrison LM, Bilguvar K, Knight JR, Humphries D, Wilson MD, Caccone A, Cappello M. Application of multiplex amplicon deep-sequencing (MAD-seq) to screen for putative drug resistance markers in the Necator americanus isotype-1 β-tubulin gene. Scientific Reports 2022, 12: 11459. PMID: 35794459, PMCID: PMC9259660, DOI: 10.1038/s41598-022-15718-1.Peer-Reviewed Original ResearchConceptsSingle nucleotide polymorphismsPeriodic mass drug administrationHigh-risk groupCross-sectional studyDrug resistance markersMass drug administrationResistance-associated mutationsHookworm Necator americanusPost-treatment samplesIsotype-1 β-tubulin geneHookworm infectionPersistent infectionResistance markersDrug AdministrationNecator americanusInfection statusVeterinary nematodesInfectionMarkersNucleotide polymorphismsSensitive toolBenzimidazole drugsNucleotide alleles
2019
Necator Americanus and Plasmodium Falciparum Co-Infection and Albendazole Treatment Outcome among Individuals in Rural Ghana
Amoani B, Adu B, Frempong M, Barnes P, Cappello M, Gyan B, Wilson M. Necator Americanus and Plasmodium Falciparum Co-Infection and Albendazole Treatment Outcome among Individuals in Rural Ghana. The Journal Of Advances In Parasitology 2019, 6 DOI: 10.17582/journal.jap/2019/6.4.51.54.Peer-Reviewed Original Research