Featured Publications
Contribution of Individual Diseases to Death in Older Adults with Multiple Diseases
Tinetti ME, McAvay GJ, Murphy TE, Gross CP, Lin H, Allore HG. Contribution of Individual Diseases to Death in Older Adults with Multiple Diseases. Journal Of The American Geriatrics Society 2012, 60: 1448-1456. PMID: 22734792, PMCID: PMC3419332, DOI: 10.1111/j.1532-5415.2012.04077.x.Peer-Reviewed Original ResearchConceptsOlder adultsSingle underlying causeRespiratory diseaseMedicare Current Beneficiary Survey participantsChronic lower respiratory diseasesUnderlying causeAcute kidney injuryLower respiratory diseaseAverage attributable fractionKidney injuryHazard ratioHeart failureLiver diseaseAcute eventMyocardial infarctionUnintentional injuriesAcute diseaseAttributable fractionNational representative sampleMedicare beneficiariesOlder adults' experiencesDiseaseIndividual diseasesDeathConfidence intervalsContribution of Multiple Chronic Conditions to Universal Health Outcomes
Tinetti ME, McAvay GJ, Chang SS, Newman AB, Fitzpatrick AL, Fried TR, Peduzzi PN. Contribution of Multiple Chronic Conditions to Universal Health Outcomes. Journal Of The American Geriatrics Society 2011, 59: 1686-1691. PMID: 21883118, PMCID: PMC3622699, DOI: 10.1111/j.1532-5415.2011.03573.x.Peer-Reviewed Original ResearchConceptsChronic obstructive pulmonary diseaseUniversal health outcomesHeart failureSelf-rated healthCognitive impairmentHealth outcomesChronic conditionsObstructive pulmonary diseaseCardiovascular Health StudyCommunity-living participantsMultiple chronic conditionsPulmonary diseaseBurden ScaleInstrumental activitiesDaily livingCox modelHealth StudyCare prioritiesMore symptomsIADLsDepressionImpairmentOutcomesOsteoarthritisADLsEffect of Chronic Disease–Related Symptoms and Impairments on Universal Health Outcomes in Older Adults
Tinetti ME, McAvay G, Chang SS, Ning Y, Newman AB, Fitzpatrick A, Fried TR, Harris TB, Nevitt MC, Satterfield S, Yaffe K, Peduzzi P. Effect of Chronic Disease–Related Symptoms and Impairments on Universal Health Outcomes in Older Adults. Journal Of The American Geriatrics Society 2011, 59: 1618-1627. PMID: 21883120, PMCID: PMC3287052, DOI: 10.1111/j.1532-5415.2011.03576.x.Peer-Reviewed Original ResearchConceptsUniversal health outcomesChronic obstructive pulmonary diseaseCardiovascular Health StudyHeart failureDisease-related symptomsEjection fractionHF symptomsSelf-rated healthHealth outcomesChronic diseasesCognitive impairmentObstructive pulmonary diseaseBody Composition StudyTarget of therapyDyspnea scaleExpiratory volumeHazard ratioJoint painPulmonary diseaseInstrumental activitiesDaily livingHealth StudyDisease severitySignificant associationSymptoms
2015
Association between guideline recommended drugs and death in older adults with multiple chronic conditions: population based cohort study
Tinetti ME, McAvay G, Trentalange M, Cohen AB, Allore HG. Association between guideline recommended drugs and death in older adults with multiple chronic conditions: population based cohort study. The BMJ 2015, 351: h4984. PMID: 26432468, PMCID: PMC4591503, DOI: 10.1136/bmj.h4984.Peer-Reviewed Original ResearchConceptsSerotonin-norepinephrine reuptake inhibitorsMultiple chronic conditionsSelective serotonin reuptake inhibitorsAdjusted hazard ratioRisk of deathCalcium channel blockersChronic conditionsHazard ratioΒ-blockersCohort studyReuptake inhibitorsAtrial fibrillationOlder adultsChannel blockersCardiovascular drugsSSRIs/serotonin-norepinephrine reuptake inhibitorsRenin-angiotensin system blockersNorepinephrine reuptake inhibitorsSerotonin reuptake inhibitorsCommon combinationRAS blockersSystem blockersStudy drugHeart failureThromboembolic disease
1999
Older persons’ perceptions of home and hospital as sites of treatment for acute illness
Fried T, van Doorn C, O’Leary J, Tinetti M, Drickamer M. Older persons’ perceptions of home and hospital as sites of treatment for acute illness. The American Journal Of Medicine 1999, 107: 317-323. PMID: 10527032, DOI: 10.1016/s0002-9343(99)00236-3.Peer-Reviewed Original ResearchConceptsAcute illnessChronic obstructive pulmonary diseasePersons age 65 yearsCongestive heart failureObstructive pulmonary diseaseHome careAge 65 yearsOlder patients' perceptionsEfficacy of treatmentAcute home careSite of treatmentSelf-rated healthPatient characteristicsHeart failurePulmonary diseaseAcute careHospital treatmentDependent patientsPrimary diagnosisPatients' perceptionsHome treatmentUse of homeHospital careOlder persons' perceptionsHospitalOlder persons' preferences for site of terminal care.
Fried T, Doorn C, O'Leary J, Tinetti M, Drickamer M. Older persons' preferences for site of terminal care. Annals Of Internal Medicine 1999, 131: 109-12. PMID: 10419426, DOI: 10.7326/0003-4819-131-2-199907200-00006.Peer-Reviewed Original ResearchConceptsTerminal careOlder persons' preferencesCommunity-dwelling persons 65 yearsChronic obstructive pulmonary diseaseCongestive heart failureObstructive pulmonary diseasePersons 65 yearsSite of careLong-term care needsCare of disabilitiesFamily membersNonterminal illnessHeart failurePulmonary diseaseQuantitative interviewsPatient preferencesLife careCare needsNursing homesQualitative interviewsTerminal illnessParticipants' homesOlder personsHospitalCare
1998
Older Persons’ Preferences for Site of Treatment in Acute Illness. ANNOUNCEMENT
Fried T, Van Doorn C, Tinetti M, Drickamer M. Older Persons’ Preferences for Site of Treatment in Acute Illness. ANNOUNCEMENT. Journal Of General Internal Medicine 1998, 13: 522-527. PMID: 9734788, PMCID: PMC1496998, DOI: 10.1046/j.1525-1497.1998.00162.x.Peer-Reviewed Original ResearchConceptsAcute illnessHome care servicesHome treatmentHome careCare servicesChronic obstructive pulmonary diseaseCongestive heart failureObstructive pulmonary diseaseProcess of careLower intensity servicesSite of treatmentOlder persons' preferencesPersons age 65Health care systemHeart failurePulmonary diseasePatient preferencesHospital careMedical careAge 65Older personsHospitalIllness experienceCare systemCareMODELS OF GERIATRICS PRACTICE: When the Patient Cannot Come to the Doctor: A Medical Housecalls Program
Reuben D, Fried T, Wachtel T, Tinetti M. MODELS OF GERIATRICS PRACTICE: When the Patient Cannot Come to the Doctor: A Medical Housecalls Program. Journal Of The American Geriatrics Society 1998, 46: 226-231. PMID: 9475454, DOI: 10.1111/j.1532-5415.1998.tb02544.x.Peer-Reviewed Original ResearchConceptsUpper respiratory tract infectionFrail older patientsRespiratory tract infectionsCongestive heart failureMajority of patientsRoutine medical careSevere cognitive impairmentGERIATRICS PRACTICEAcute illnessOlder patientsTract infectionsHeart failureHomebound patientsUnscheduled visitsEmergency roomNurse practitionersDaily livingMedical residency programsPatientsPatient's homeScheduled visitsAmbulatory practiceCognitive impairmentComplex illnessMedical care