2020
Adverse Drug Effects in Patients with CKD: Primum Non Nocere.
Perazella MA, Nolin TD. Adverse Drug Effects in Patients with CKD: Primum Non Nocere. Clinical Journal Of The American Society Of Nephrology 2020, 15: 1075-1077. PMID: 32611663, PMCID: PMC7409750, DOI: 10.2215/cjn.08890620.Peer-Reviewed Original ResearchDrug-Related Side Effects and Adverse ReactionsGlomerular Filtration RateHumansPharmaceutical PreparationsRenal Insufficiency, ChronicRenin-Angiotensin System
2015
Drug-Induced Glomerular Disease: Direct Cellular Injury
Markowitz GS, Bomback AS, Perazella MA. Drug-Induced Glomerular Disease: Direct Cellular Injury. Clinical Journal Of The American Society Of Nephrology 2015, 10: 1291-1299. PMID: 25862776, PMCID: PMC4491280, DOI: 10.2215/cjn.00860115.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsDrug-Related Side Effects and Adverse ReactionsEndothelial CellsEpithelial CellsGlomerulonephritisHumansKidney GlomerulusMesangial CellsPrognosisRisk AssessmentRisk FactorsConceptsGlomerular diseaseCell injuryGlomerular lesionsNonsteroidal anti-inflammatory drugsAcute interstitial nephritisDrug-induced etiologyPotential of medicationsRenal function recoveryAcute tubular necrosisEndothelial cell injuryMesangial cell injuryEpithelial cell injuryAnti-inflammatory drugsDirect cellular injuryRapid discontinuationKidney injuryTubular necrosisAntiplatelet agentsInterstitial nephritisTubulointerstitial compartmentFunction recoveryIatrogenic formCellular injuryAntiangiogenesis drugsInjury
2009
Renal Vulnerability to Drug Toxicity
Perazella MA. Renal Vulnerability to Drug Toxicity. Clinical Journal Of The American Society Of Nephrology 2009, 4: 1275-1283. PMID: 19520747, DOI: 10.2215/cjn.02050309.Peer-Reviewed Original ResearchConceptsDrug-induced kidney diseaseKidney diseaseRenal vulnerabilityRisk factorsAcute kidney injuryChronic kidney diseaseDrug-related factorsProteinuric renal diseaseKidney injuryRenal complicationsRenal injuryRenal diseaseNephrotoxic effectsRenal syndromeDrug toxicityDiseaseInjuryKidneyDrugsFactor categoriesToxinComplicationsPatientsFactorsTubulopathy
2000
Drug-induced hyperkalemia: old culprits and new offenders
Perazella M. Drug-induced hyperkalemia: old culprits and new offenders. The American Journal Of Medicine 2000, 109: 307-314. PMID: 10996582, DOI: 10.1016/s0002-9343(00)00496-4.Peer-Reviewed Original ResearchMeSH KeywordsDietary SupplementsDrug-Related Side Effects and Adverse ReactionsFemaleHumansHyperkalemiaKidneyMaleNonprescription DrugsPotassiumPrimary PreventionPrognosisRisk AssessmentConceptsDrug-induced hyperkalemiaRisk of hyperkalemiaRenal potassium excretionRenal impairmentPatient characteristicsPotassium excretionPotassium handlingPotassium loadPrescribed medicationsExcessive ingestionHyperkalemiaCounter drugsOld culpritsNutritional supplementsPotassium homeostasisMedicationsPatientsDrugsCellular uptakeInfusionAbnormalitiesExcretionPhysiciansImpairmentIngestion
1997
Hyperkalemia in the Elderly
Perazella M, Mahnensmith R. Hyperkalemia in the Elderly. Journal Of General Internal Medicine 1997, 12: 646-656. PMID: 9346463, PMCID: PMC1497179, DOI: 10.1046/j.1525-1497.1997.07128.x.Peer-Reviewed Original ResearchMeSH KeywordsAgedAgingDrug-Related Side Effects and Adverse ReactionsFemaleHomeostasisHumansHyperkalemiaHypoaldosteronismIncidenceMalePotassiumPrognosisRisk FactorsConceptsDevelopment of hyperkalemiaPotassium-altering medicationsAppropriate managementPrevention of hyperkalemiaHigh-risk medicationsManagement of hyperkalemiaCellular potassium uptakePlasma potassium concentrationPertinent review articlesCardiac complicationsElderly patientsPotassium handlingRenal functionSevere hyperkalemiaCertain medicationsElectrolyte disordersGeriatric patientsClinical manifestationsElderly subjectsMEDLINE searchHyperkalemiaMedicationsDisease processRenal disposalPotassium levels