2016
Posttranslational modification of islet autoantigens in type 1 diabetes
Yang M, Wen L, Herold K, Mamula M. Posttranslational modification of islet autoantigens in type 1 diabetes. The Journal Of Immunology 2016, 196: 118.9-118.9. DOI: 10.4049/jimmunol.196.supp.118.9.Peer-Reviewed Original ResearchAnti-insulin autoimmunityType 1 diabetesNon-obese diabetic (NOD) micePrediabetic NOD miceDevelopment of T1D.Onset of hyperglycemiaHuman pancreatic isletsNOD miceHuman T1DHuman T1D.Islet autoantigensImmune toleranceAutoimmune responseDiabetic miceAutoimmune diseasesInflammatory cytokinesTissue pathologyPancreatic isletsAutoantibodiesT1D.Islet proteinsAutoantigensOxidative stressInsulin biosynthesisAutoimmunity
2011
Chapter 8 B-Lymphocyte Biology in SLE
Mamula M. Chapter 8 B-Lymphocyte Biology in SLE. 2011, 143-161. DOI: 10.1016/b978-0-12-374994-9.10008-7.Peer-Reviewed Original ResearchSystemic lupus erythematosusHuman systemic lupus erythematosusAntigen-presenting cellsB cellsDiagnostic hallmarkAutoreactive B cell responsesB-cell-specific therapiesClinical systemic lupus erythematosusB lymphocyte subsetsIgG class autoantibodiesB cell responsesT lymphocyte interactionsMultiple cellular abnormalitiesDendritic cellsLupus erythematosusAutoantibody responseLupus autoantigensClass autoantibodiesT cellsMurine modelB lymphocyte biologyGenetic predispositionReceptor inductionPathologic processesTissue pathology