2024
Cohort study of patients with advanced cancer: outcomes associated with duration of antibiotic therapy for non-ventilator hospital-acquired pneumonia
Lee S, Benson J, Cohen A, Quagliarello V, Juthani-Mehta M, Datta R. Cohort study of patients with advanced cancer: outcomes associated with duration of antibiotic therapy for non-ventilator hospital-acquired pneumonia. Antimicrobial Stewardship & Healthcare Epidemiology 2024, 4: e48. PMID: 38655023, PMCID: PMC11036428, DOI: 10.1017/ash.2024.54.Peer-Reviewed Original ResearchNon-ventilator hospital-acquired pneumoniaAdvanced cancerPalliative care settingHospital-acquired pneumoniaCohort study of patientsCare settingsOlder adultsAdjusted oddsDuration of antibiotic therapyAssociated with reduced adjusted oddsSingle-center observational studyCohort studyProlonged antibiotic durationObservational studyStudy of patientsAntimicrobial stewardship effortsAntibiotic durationAntibiotic therapyStewardship effortsPneumoniaCancerOddsReadmissionAdultsCohort
2023
Antibiotic therapy is associated with adverse drug events among older adults with advanced cancer: A cohort study
Datta R, Han L, Doyle M, Allore H, Sanft T, Quagliarello V, Juthani-Mehta M. Antibiotic therapy is associated with adverse drug events among older adults with advanced cancer: A cohort study. Palliative Medicine 2023, 37: 793-798. PMID: 36999898, DOI: 10.1177/02692163231162889.Peer-Reviewed Original ResearchConceptsAdverse drug eventsAntibiotic therapyDrug eventsAdvanced cancerOlder adultsIndex admissionPalliative chemotherapyCohort studyTertiary care centerHospitalized older adultsPalliative care providersMultidrug-resistant organismsMean ageCommon tumorsCare centerCare providersRatio of daysSolid tumorsMultivariable testingPatientsTherapyStandardized criteriaCancerMean timeAdults
2022
Prevalence and treatment of postobstructive pneumonia among older adults with advanced cancer
Lee S, O’Donovan L, Cohen A, Gautam S, Quagliarello V, Juthani-Mehta M, Datta R. Prevalence and treatment of postobstructive pneumonia among older adults with advanced cancer. Antimicrobial Stewardship & Healthcare Epidemiology 2022, 2: e152. PMID: 36483405, PMCID: PMC9726473, DOI: 10.1017/ash.2022.293.Peer-Reviewed Original Research
2020
Education needed to improve antimicrobial use during end-of-life care of older adults with advanced cancer: A cross-sectional survey
Datta R, Topal J, McManus D, Sanft T, Dembry LM, Morrison LJ, Quagliarello V, Juthani-Mehta M. Education needed to improve antimicrobial use during end-of-life care of older adults with advanced cancer: A cross-sectional survey. Palliative Medicine 2020, 35: 236-241. PMID: 32928066, DOI: 10.1177/0269216320956811.Peer-Reviewed Original ResearchConceptsEscalation of careAdvance care planningLife careAdvanced cancerCross-sectional surveyIntravenous antimicrobialsOlder adultsAntimicrobial useCare planningSingle-center cross-sectional surveyEducational interventionAdvance care plansRole of antimicrobialsClinical deteriorationPercent of respondentsAdverse eventsOral antimicrobialsMedicine subspecialistsCare plansInpatient medicineCareCancerPatientsAdultsSubspecialistsAdverse Events and Healthcare Utilization Associated With Outpatient Parenteral Antimicrobial Therapy Among Older Versus Younger Adults
Brzozowski K, Datta R, Canterino J, Malinis M, Juthani-Mehta M. Adverse Events and Healthcare Utilization Associated With Outpatient Parenteral Antimicrobial Therapy Among Older Versus Younger Adults. Open Forum Infectious Diseases 2020, 7: ofaa358. PMID: 33094112, PMCID: PMC7566523, DOI: 10.1093/ofid/ofaa358.Peer-Reviewed Original Research
2013
Diagnosis and Management of Urinary Tract Infection in Older Adults
Rowe TA, Juthani-Mehta M. Diagnosis and Management of Urinary Tract Infection in Older Adults. Infectious Disease Clinics Of North America 2013, 28: 75-89. PMID: 24484576, PMCID: PMC4079031, DOI: 10.1016/j.idc.2013.10.004.Peer-Reviewed Original ResearchUrinary tract infection in older adults
Rowe TA, Juthani-Mehta M. Urinary tract infection in older adults. Aging Health 2013, 9: 519-528. PMID: 24391677, PMCID: PMC3878051, DOI: 10.2217/ahe.13.38.Peer-Reviewed Original ResearchUrinary tract infectionTract infectionsAsymptomatic bacteriuriaOlder adultsSymptomatic urinary tract infectionLong-term care facilitiesMultidrug-resistant organismsEvidence-based approachGenitourinary symptomsGold standard definitionConsensus guidelinesDiagnostic challengeCare facilitiesInfectionBacteriuriaDiagnostic accuracyYoung adultsDiagnosisAdultsCliniciansFuture studiesStandard definitionSignificant problemSymptomsPrevalence
2009
Bronchitis and Pneumonia
Juthani-Mehta M, Quagliarello V. Bronchitis and Pneumonia. Infectious Disease 2009, 81-95. PMCID: PMC7121308, DOI: 10.1007/978-1-60327-534-7_7.Peer-Reviewed Original ResearchOlder adultsOral hygieneLong-term care residentsPoor oral hygieneChest X-rayLack of vaccinationSite of careUnique risk factorsEmpirical treatment decisionsMultiple comorbiditiesClinical entityClinical manifestationsMental statusRisk factorsHome therapyHome residentsTreatment decisionsCare residentsCommunity dwellersPneumoniaBetter outcomesNursing homesPrevention strategiesBronchitisAdults
2007
Asymptomatic Bacteriuria and Urinary Tract Infection in Older Adults
Juthani-Mehta M. Asymptomatic Bacteriuria and Urinary Tract Infection in Older Adults. Clinics In Geriatric Medicine 2007, 23: 585-594. PMID: 17631235, DOI: 10.1016/j.cger.2007.03.001.Peer-Reviewed Original Research
2004
Prognostic Scoring Systems for Infectious Diseases: Their Applicability to the Care of Older Adults
High K, Juthani-Mehta M, Quagliarello V. Prognostic Scoring Systems for Infectious Diseases: Their Applicability to the Care of Older Adults. Clinical Infectious Diseases 2004, 38: 692-696. PMID: 14986254, DOI: 10.1086/381688.Peer-Reviewed Original ResearchConceptsPrognostic scoring systemOlder adultsScoring systemAdult populationInfectious diseasesPrimary end pointNumber of patientsGeneral adult populationHealth care needsHealth care costsHeterogeneous adult populationClinical outcomesBloodstream infectionsIndividual patientsCare needsCare costsRelevant outcomesEnd pointClinical predictionDiseasePatientsAdultsFurther investigationCareOutcomes