2021
Macroporous scaffold surface modified with biological macromolecules and piroxicam-loaded gelatin nanofibers toward meniscus cartilage repair
Abpeikar Z, Javdani M, Mirzaei S, Alizadeh A, Moradi L, Soleimannejad M, Bonakdar S, Asadpour S. Macroporous scaffold surface modified with biological macromolecules and piroxicam-loaded gelatin nanofibers toward meniscus cartilage repair. International Journal Of Biological Macromolecules 2021, 183: 1327-1345. PMID: 33932422, DOI: 10.1016/j.ijbiomac.2021.04.151.Peer-Reviewed Original ResearchConceptsAdipose-derived mesenchymal stem cellsChondrocyte marker genesRabbit adipose-derived mesenchymal stem cellsHigh expression levelsNative meniscus tissueGelatin nanofibersMarker genesSurface-modified scaffoldsGene expressionCompressive Young's modulusMesenchymal stem cellsCell migrationDAPI stainingMeniscus tissue engineeringDegradation rateSelf-healing capacityStem cellsExpression levelsCell-seeded scaffoldsMechanical testsScaffold surfaceYoung's modulusPoor self-healing capacityBiological macromoleculesViability assays
2016
Epidermal growth factor receptor targeting alters gene expression and restores the adhesion function of cancerous cells as measured by single cell force spectroscopy
Azadi S, Tafazzoli-Shadpour M, Omidvar R, Moradi L, Habibi-Anbouhi M. Epidermal growth factor receptor targeting alters gene expression and restores the adhesion function of cancerous cells as measured by single cell force spectroscopy. Molecular And Cellular Biochemistry 2016, 423: 129-139. PMID: 27696309, DOI: 10.1007/s11010-016-2831-x.Peer-Reviewed Original ResearchConceptsCell-cell adhesionE-cadherin expressionEpidermal growth factor receptorGrowth factor receptorAdhesion functionCell-cell adhesion forcesCell-cell adhesion functionSingle-cell force spectroscopyFactor receptorAlters gene expressionCell force spectroscopyE-cadherin geneTime PCR analysisBlockade of EGFRTreatment of cellsForce spectroscopy techniquesHuman epithelial cancer cell linesEpithelial cancer cell linesCancerous cellsCell mechanical propertiesEGFR activityGene expressionCell behaviorInhibition of metastasisCancer progression