Serum Lipoproteins Are Associated With Coronary Atherosclerosis in Asymptomatic U.S. Adults Without Traditional Risk Factors
Faridi K, Lahan S, Budoff M, Cury R, Feldman T, Pan A, Fialkow J, Nasir K. Serum Lipoproteins Are Associated With Coronary Atherosclerosis in Asymptomatic U.S. Adults Without Traditional Risk Factors. JACC Advances 2024, 3: 101049. PMID: 39129991, PMCID: PMC11312344, DOI: 10.1016/j.jacadv.2024.101049.Peer-Reviewed Original ResearchTraditional risk factorsNon-HDL-CLDL-CRisk factorsAssociated with atherosclerosisCoronary atherosclerosisLipoprotein cholesterolAtherosclerotic cardiovascular disease riskSerum non-HDL-COptimal risk factorsLow-risk adultsActive tobacco useCardiovascular disease riskAssociation of low-density lipoprotein cholesterolAsymptomatic middle-aged adultsNon-high-density lipoprotein cholesterolAtherosclerosis prevalenceCoronary computed tomography angiographyHigh-risk plaque featuresMiddle-aged adultsAtherogenic lipoproteinsHigh LDL-CLow-density lipoprotein cholesterolLevels of atherogenic lipoproteinsMultivariate logistic regressionPragmatic Trial of Messaging to Providers About Treatment of Hyperlipidemia (PROMPT-LIPID): A Randomized Clinical Trial
Shah N, Ghazi L, Yamamoto Y, Kumar S, Martin M, Simonov M, Riello Iii R, Faridi K, Ahmad T, Wilson F, Desai N. Pragmatic Trial of Messaging to Providers About Treatment of Hyperlipidemia (PROMPT-LIPID): A Randomized Clinical Trial. Circulation Cardiovascular Quality And Outcomes 2024, 17: e010335. PMID: 38634282, DOI: 10.1161/circoutcomes.123.010335.Peer-Reviewed Original ResearchElectronic health recordsElectronic health record alertsHigh-risk atherosclerotic cardiovascular diseaseLipid lowering therapyAtherosclerotic cardiovascular diseasePragmatic trialCardiovascular diseaseProportion of patientsYale New Haven HealthLDL-CSecondary outcomesPrimary outcomeInternal medicine cliniciansEHR alertUsual careHealth recordsProvider levelCluster-randomizedLDL-C managementLDL-C levelsAdverse cardiovascular eventsRandomized clinical trialsTreatment of hyperlipidemiaCliniciansCardiovascular events