2023
Megahertz Sampling of Prestin (SLC26a5) Voltage-Sensor Charge Movements in Outer Hair Cell Membranes Reveals Ultrasonic Activity that May Support Electromotility and Cochlear Amplification
Santos-Sacchi J, Bai J, Navaratnam D. Megahertz Sampling of Prestin (SLC26a5) Voltage-Sensor Charge Movements in Outer Hair Cell Membranes Reveals Ultrasonic Activity that May Support Electromotility and Cochlear Amplification. Journal Of Neuroscience 2023, 43: 2460-2468. PMID: 36868859, PMCID: PMC10082455, DOI: 10.1523/jneurosci.2033-22.2023.Peer-Reviewed Original ResearchConceptsConformational switchingMammalian hearingMembrane motor proteinCochlear amplificationMotor protein prestinVoltage-sensor charge movementOuter hair cell electromotilityHair cell electromotilityProtein prestinMotor proteinsConformation switchingCharge movementPrestinPrestin activityCell membraneOHC electromotilityHair cell membraneElectromotilityTransmembrane voltageOrgan of CortiAmplificationMammalsMembrane capacitanceProtein
2019
The speed limit of outer hair cell electromechanical activity
Santos-Sacchi J. The speed limit of outer hair cell electromechanical activity. HNO 2019, 67: 159-164. PMID: 30747242, DOI: 10.1007/s00106-019-0615-9.Peer-Reviewed Original Research
2008
Cochlear Mechanics: No Shout but a Twist in the Absence of Prestin
Santos-Sacchi J. Cochlear Mechanics: No Shout but a Twist in the Absence of Prestin. Current Biology 2008, 18: r304-r306. PMID: 18397741, DOI: 10.1016/j.cub.2008.02.019.Peer-Reviewed Original Research