2023
Single-cell atlas of the human neonatal small intestine affected by necrotizing enterocolitis
Egozi A, Olaloye O, Werner L, Silva T, McCourt B, Pierce R, An X, Wang F, Chen K, Pober J, Shouval D, Itzkovitz S, Konnikova L. Single-cell atlas of the human neonatal small intestine affected by necrotizing enterocolitis. PLOS Biology 2023, 21: e3002124. PMID: 37205711, PMCID: PMC10234541, DOI: 10.1371/journal.pbio.3002124.Peer-Reviewed Original ResearchConceptsSingle-cell RNA sequencingSingle-cell atlasEpithelial cellsCell identityRNA sequencingBulk transcriptomicsCellular dysregulationAberrant interactionsNeonatal small intestinePotential targetCellular changesBiomarker discoveryGastrointestinal complicationsPremature infantsProinflammatory macrophagesProinflammatory genesClonal expansionT cellsEndothelial cellsImmune interactionsIntestinal tissueCellsSmall intestineComprehensive viewNEC
2007
Tumor Necrosis Factor
Pober J. Tumor Necrosis Factor. 2007, 261-265. DOI: 10.1017/cbo9780511546198.032.Peer-Reviewed Original ResearchHemorrhagic necrosisNecrosis factorMediator of cachexiaMediators of inflammationTumor necrosis factorPrimary cellular sourceAdaptive immune systemTNF-like moleculeTime of cloningMajor histocompatibility complexPeyer's patchesEndogenous mediatorsT lymphocytesMast cellsParasitic infectionsTNFBacterial productsExperimental tumorsImmune systemMononuclear phagocytesCellular sourceSmall intestineHistocompatibility complexTNF geneRelated receptors