2003
Identification of the primary caspase 3 cleavage site in alpha II-spectrin during apoptosis
Williams S, Smith A, Cianci C, Morrow J, Brown T. Identification of the primary caspase 3 cleavage site in alpha II-spectrin during apoptosis. Apoptosis 2003, 8: 353-361. PMID: 12815278, DOI: 10.1023/a:1024168901003.Peer-Reviewed Original ResearchConceptsCaspase-3 cleavage siteCleavage sitePrimary cleavage siteII-spectrinCytoskeletal integrityAlpha II spectrinMembrane stabilityCaspase-3Cleavage of alphaApoptotic cell deathCaspase-3 activationMature B cellsConsensus sitesDeletion analysisTranscriptional inhibitorMajor proteinsLikely altersApoptotic bodiesCell deathProteinStructural conformationActinomycin DSpectrinNew insightsApoptosis
1997
Of Membrane Stability and Mosaics: The Spectrin Cytoskeleton
Morrow J, Rimm D, Kennedy S, Cianci C, Sinard J, Weed S. Of Membrane Stability and Mosaics: The Spectrin Cytoskeleton. 1997, 485-540. DOI: 10.1002/cphy.cp140111.Peer-Reviewed Original ResearchNon-erythroid cellsMembrane skeletonRed cell membrane skeletonSpectrin membrane skeletonCell membrane skeletonErythrocyte membrane skeletonMembrane organizersProtein 4.1Spectrin cytoskeletonAdhesion proteinsCytoskeletal elementsSpectrin skeletonMembrane stabilityMosaic modelSpectrinProteinCellsDematinDynaminStomatinPallidinCytoskeletonAnkyrinAdducinTropomodulin
1996
Chapter 6 The Spectrin Cytoskeleton and Organization of Polarized Epithelial Cell Membranes
Devarajan P, Morrow J. Chapter 6 The Spectrin Cytoskeleton and Organization of Polarized Epithelial Cell Membranes. Current Topics In Membranes 1996, 43: 97-128. DOI: 10.1016/s0070-2161(08)60386-x.Peer-Reviewed Original ResearchIntegral membrane proteinsPeripheral plasma membraneCultured epithelial cellsEpithelial cellsAnti-spectrin antibodiesEukaryotic cellsNonerythroid cellsMembrane proteinsSpectrin cytoskeletonEpithelial cell membranesPlasma membraneExperimental removalCell shapeDifferent isoformsMembrane stabilitySpectrinCell membraneCytoskeletonPostsynaptic densityPostsynaptic membraneMembrane instabilityCerebellar granule cellsSkeletal muscleMembraneCells