2024
The role of anatomic shape features in the prognosis of uncomplicated type B aortic dissection initially treated with optimal medical therapy
Liu M, Dong H, Mazlout A, Wu Y, Kalyanasundaram A, Oshinski J, Sun W, Elefteriades J, Leshnower B, Gleason R. The role of anatomic shape features in the prognosis of uncomplicated type B aortic dissection initially treated with optimal medical therapy. Computers In Biology And Medicine 2024, 170: 108041. PMID: 38330820, PMCID: PMC10932856, DOI: 10.1016/j.compbiomed.2024.108041.Peer-Reviewed Original ResearchConceptsType B aortic dissectionTreated with optimal medical therapyAortic growth rateOptimal medical therapyUncomplicated type B aortic dissectionB aortic dissectionMedical therapyCT scanPatients' long-term survivalType B aortic dissection patientsLong-term outcomesLong-term survivalFailure groupAortic expansionChronic phaseFailure patientsPatientsCT imagesTherapyDissectionStatistical shape modelFailurePrognosisScanningRegression
2016
Neurological Events Following Transcatheter Aortic Valve Replacement and Their Predictors
Kleiman N, Maini B, Reardon M, Conte J, Katz S, Rajagopal V, Kauten J, Hartman A, McKay R, Hagberg R, Huang J, Popma J, Adams D, Ad N, Aharonian V, Anderson W, Applegate R, Bafi A, Bajwa T, Bakhos M, Ball S, Batra S, Beohar N, Brachinsky W, Brinster D, Brown J, Byrne J, Byrne T, Casale A, Caskey M, Chawla A, Cohen H, Coselli J, Costa M, Cheatham J, Chetcuti S, Crestanello J, Davis T, Michael Deeb G, Diez J, Dauerman H, Elefteriades J, Fail P, Feinberg E, Fontana G, Forrest J, Galloway A, Giacomini J, Gleason T, Guadiani V, Harrison J, Hebeler R, Heimansohn D, Heiser J, Heller L, Henry S, Hermiller J, Hockmuth D, Hughes G, Joye J, Kafi A, Kar B, Khabbaz K, Kipperman R, Kliger C, Kon N, Lamelas J, Lee J, Leya F, Londono J, Macheers S, Mangi A, de Marchena E, Markowitz A, Matthews R, Merhi W, Mumtaz M, O’Hair D, Petrossian G, Pfeffer T, Raybuck B, Resar J, Robbins M, Robbins R, Robinson N, Ring M, Salerno T, Schreiber T, Schmoker J, Sharma S, Siwek L, Skelding K, Slater J, Starnes V, Stoler R, Subramanian V, Tadros P, Thompson C, Waksman R, Watson D, Yakubov S, Zhao D, Zorn G. Neurological Events Following Transcatheter Aortic Valve Replacement and Their Predictors. Circulation Cardiovascular Interventions 2016, 9: e003551. PMID: 27601429, DOI: 10.1161/circinterventions.115.003551.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAortic ValveAortic Valve StenosisBalloon ValvuloplastyBioprosthesisCalcinosisCardiac Pacing, ArtificialClinical Trials as TopicFemaleHeart Valve ProsthesisHumansIncidenceIntracranial EmbolismKaplan-Meier EstimateMaleProportional Hazards ModelsRisk AssessmentRisk FactorsSeverity of Illness IndexStrokeTime FactorsTranscatheter Aortic Valve ReplacementTreatment OutcomeConceptsTranscatheter aortic valve replacementAortic valve replacementValve replacementEarly strokePrior coronary artery bypass surgeryHealth Stroke Scale scoreSelf-expanding CoreValve bioprosthesisCoronary artery bypass surgerySmaller body surface areaLower body mass indexContinued Access StudySevere aortic calcificationStroke Scale scoreTransient ischemic attackArtery bypass surgeryPeripheral vascular diseasePredictors of strokeBody mass indexBody surface areaIdentification of predictorsCoreValve bioprosthesisIschemic attackPrior strokeBypass surgeryAortic calcification
2009
Deep Hypothermic Circulatory Arrest in Patients With High Cognitive Needs: Full Preservation of Cognitive Abilities
Percy A, Widman S, Rizzo JA, Tranquilli M, Elefteriades JA. Deep Hypothermic Circulatory Arrest in Patients With High Cognitive Needs: Full Preservation of Cognitive Abilities. The Annals Of Thoracic Surgery 2009, 87: 117-123. PMID: 19101283, DOI: 10.1016/j.athoracsur.2008.10.025.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAorta, ThoracicAortic Aneurysm, ThoracicBlood Vessel Prosthesis ImplantationCase-Control StudiesCirculatory Arrest, Deep Hypothermia InducedCognitionCognition DisordersFemaleFollow-Up StudiesHumansMaleMiddle AgedPatient SatisfactionPostoperative CarePreoperative CareProbabilityPsychometricsRadiographyReference ValuesRetrospective StudiesRisk AssessmentSurveys and QuestionnairesTreatment OutcomeVascular Surgical ProceduresConceptsDeep hypothermic circulatory arrestHypothermic circulatory arrestAortic surgeryCirculatory arrestStudy groupStraight deep hypothermic circulatory arrestYale-New Haven HospitalOpen distal anastomosisThoracic aortic surgeryTotal arch replacementArch replacementCerebral protectionPreoperative statusDistal anastomosisSuch patientsFunctional outcomeControl subjectsPatientsSurgeryControl groupAdverse effectsSignificant differencesCognitive changesDaily activitiesOverall score
2007
What Is the Optimal Management of Late-Presenting Survivors of Acute Type A Aortic Dissection?
Davies RR, Coe MP, Mandapati D, Gallo A, Botta DM, Elefteriades JA, Coady MA. What Is the Optimal Management of Late-Presenting Survivors of Acute Type A Aortic Dissection? The Annals Of Thoracic Surgery 2007, 83: 1593-1602. PMID: 17462364, DOI: 10.1016/j.athoracsur.2006.12.018.Peer-Reviewed Original ResearchConceptsLong-term survivalOperative repairAortic dissectionGroup AAcute Type A Aortic DissectionType A Aortic DissectionImproved long-term survivalOptimal managementExcellent long-term resultsA Aortic DissectionInitial medical managementCongestive heart failureCoronary artery diseaseOnset of symptomsLong-term resultsImmediate operative repairAcute typeSurgical emergencySymptom onsetArtery diseaseHeart failurePulmonary diseaseMedical managementSingle institutionGroup B
2001
Myocardial Revascularization as a Therapeutic Strategy in the Patient with Advanced Ventricular Dysfunction
Mitropoulos F, Elefteriades J. Myocardial Revascularization as a Therapeutic Strategy in the Patient with Advanced Ventricular Dysfunction. Heart Failure Reviews 2001, 6: 163-175. PMID: 11391034, DOI: 10.1023/a:1011416929501.Peer-Reviewed Original ResearchConceptsCoronary artery bypassVentricular dysfunctionArtery bypassPerioperative managementEjection fractionPatient selectionAdvanced ventricular dysfunctionRight ventricular dysfunctionLeft ventricular dysfunctionLow ejection fractionOptimal perioperative managementSevere ventricular dysfunctionCareful patient selectionCoronary artery diseaseLong-term outcomesNumber of patientsQuality of lifeSurgical revascularizationHeart transplantationPulmonary hypertensionMyocardial revascularizationOverall prognosisArtery diseaseMedical managementRedo bypassSingle-clamp technique does not protect against cerebrovascular accident in coronary artery bypass grafting⋆
Kim R, Mariconda D, Tellides G, Kopf G, Dewar M, Lin Z, Elefteriades J. Single-clamp technique does not protect against cerebrovascular accident in coronary artery bypass grafting⋆. European Journal Of Cardio-Thoracic Surgery 2001, 20: 127-132. PMID: 11423285, DOI: 10.1016/s1010-7940(01)00765-5.Peer-Reviewed Original ResearchConceptsSingle-clamp techniqueCoronary artery bypassPostoperative strokeArtery bypassStroke preventionCerebrovascular accidentSide-biting aortic clampAdverse myocardial effectsCross-clamp timePostoperative adverse eventsPerioperative myocardial infarctionCoronary bypass operationsLogistic regression analysisEmbolic consequencesHospital mortalityAdverse eventsAortic clampMyocardial effectsBypass operationMyocardial infarctionMyocardial protectionClinical practiceClamp techniqueSecond surgeonStroke
2000
Effect of left ventricular volume on results of coronary artery bypass grafting
Kim R, Ugurlu B, Tereb D, Wackers F, Tellides G, Elefteriades J. Effect of left ventricular volume on results of coronary artery bypass grafting. The American Journal Of Cardiology 2000, 86: 1261-1264. PMID: 11090805, DOI: 10.1016/s0002-9149(00)01216-9.Peer-Reviewed Original ResearchConceptsCoronary artery bypassArtery bypassSignificant left ventricular dilationLeft ventricular dilationLV chamber sizeLV ejection fractionMedium-term survivalSurgical revascularizationAngina symptomsEjection fractionIschemic cardiomyopathyLV dilationVentricular dilationVentricular sizeVentricular volumePatientsSignificant reductionBypassChamber sizeDilationRevascularizationCardiomyopathySymptomsSafety of left innominate vein division during aortic arch surgery
Sudhakar C, Elefteriades J. Safety of left innominate vein division during aortic arch surgery. The Annals Of Thoracic Surgery 2000, 70: 856-858. PMID: 11016323, DOI: 10.1016/s0003-4975(00)01498-3.Peer-Reviewed Original ResearchConceptsLeft innominate veinUpper extremity edemaExtremity edemaMediastinal tumorNeurologic symptomsSignificant long-term morbidityAortic arch surgeryDistal aortic anastomosisLong-term morbidityArch replacementArch surgeryExtent of involvementMultiorgan dysfunctionInnominate veinVein divisionEarly patientsMedian sternotomyAortic anastomosisMean ageSurgical approachAortic archMediastinal structuresArm elevationPatientsLocal anatomy
1999
Failure to Improve Left Ventricular Function After Coronary Revascularization for Ischemic Cardiomyopathy Is Not Associated With Worse Outcome
Samady H, Elefteriades J, Abbott B, Mattera J, McPherson C, Wackers F. Failure to Improve Left Ventricular Function After Coronary Revascularization for Ischemic Cardiomyopathy Is Not Associated With Worse Outcome. Circulation 1999, 100: 1298-1304. PMID: 10491374, DOI: 10.1161/01.cir.100.12.1298.Peer-Reviewed Original ResearchConceptsVentricular functionIschemic cardiomyopathyGroup AHeart failure scoreLeft ventricular functionIschemic LV dysfunctionPoor patient outcomesB. Group ALack of improvementBaseline LVEFEffective revascularizationImproved LVEFCoronary revascularizationLV dysfunctionConsecutive patientsIntraoperative variablesPostoperative improvementCardiac deathLV functionPoor outcomeViable myocardiumLVEF assessmentIschemic myocardiumPatient outcomesWorse outcomesManagement of descending aortic dissection
Elefteriades J, Lovoulos C, Coady M, Tellides G, Kopf G, Rizzo J. Management of descending aortic dissection. The Annals Of Thoracic Surgery 1999, 67: 2002-2005. PMID: 10391358, DOI: 10.1016/s0003-4975(99)00428-2.Peer-Reviewed Original ResearchConceptsThoracic aortic diseaseAortic replacementAortic dissectionAortic diseaseVascular occlusionCategory of patientsEarly hospital courseTime of dissectionParaplegia rateAcute dissectionHospital coursePostoperative deathsAcute expansionPatient demographicsConsecutive patientsMultiple complicationsBenign courseMedical managementSpecific complicationsSurgical interventionClinical recordsAortic aneurysmComplicated dissectionFenestration procedureTherapy variesInterval or Permanent Nonoperative Management of Acute Type A Aortic Dissection
Scholl F, Coady M, Davies R, Rizzo J, Hammond G, Kopf G, Elefteriades J. Interval or Permanent Nonoperative Management of Acute Type A Aortic Dissection. JAMA Surgery 1999, 134: 402-406. PMID: 10199313, DOI: 10.1001/archsurg.134.4.402.Peer-Reviewed Original ResearchConceptsAcute Type A Aortic DissectionType A Aortic DissectionA Aortic DissectionAortic dissectionShort-term outcomesOperative candidatesNonoperative managementMedical therapyMedical treatmentAggressive medical therapyImmediate surgical therapyInitial operative treatmentSevere aortic insufficiencyAggressive medical treatmentGroup of patientsShort-term survivalHospital mortalityAcute typeCoronary ischemiaInitial misdiagnosisNonoperative therapySignificant comorbiditiesVascular complicationsAortic insufficiencyDefinitive operation
1996
Diaphragm Pacing with a Quadripolar Phrenic Nerve Electrode: An International Study
WEESE‐MAYER D, SILVESTRI J, KENNY A, ILBAWI M, HAUPTMAN S, LIPTON J, TALONEN P, GARCIA H, WATT J, EXNER G, BAER G, ELEFTERIADES J, PERUZZI W, ALEX C, HARLID R, VINCKEN W, DAVIS G, DECRAMER M, KUENZLE C, SÆTERHAUG A, SCHÖBER J. Diaphragm Pacing with a Quadripolar Phrenic Nerve Electrode: An International Study. Pacing And Clinical Electrophysiology 1996, 19: 1311-1319. PMID: 8880794, DOI: 10.1111/j.1540-8159.1996.tb04209.x.Peer-Reviewed Original ResearchConceptsCongenital central hypoventilation syndromeActive pediatric patientsAdult patientsTetraplegic patientsPediatric patientsIdiopathic congenital central hypoventilation syndromePhrenic nerve electrodesIncidence of complicationsCentral hypoventilation syndromeHours/dayHypoventilation syndromePatient groupCCHS patientsRegistry dataSurgical proceduresMechanical traumaPatientsAbsent functionSuccessful pacingComplicationsIncidenceNerve electrodesLongitudinal studySignificant differencesNecessary interventions
1995
Optimal timing of coronary artery bypass graft surgery after acute myocardial infarction.
Braxton J, Hammond G, Letsou G, Franco K, Kopf G, Elefteriades J, Baldwin J. Optimal timing of coronary artery bypass graft surgery after acute myocardial infarction. Circulation 1995, 92: ii66-8. PMID: 7586463, DOI: 10.1161/01.cir.92.9.66.Peer-Reviewed Original ResearchConceptsCoronary artery bypass graft surgeryAcute myocardial infarctionQ-wave infarctionArtery bypass graft surgeryNon-Q-wave infarctionBypass graft surgeryMyocardial infarctionGraft surgeryControl groupNon-Q-wave myocardial infarctionIntra-aortic balloon pumpOptimal timingGroup 1 patientsNeed of vasopressorsPerioperative myocardial infarctionWeeks of infarctionAngina refractoryPerioperative MIHospital mortalitySurgical mortalityBalloon pumpControl patientsMedical managementRelative riskHigh riskLeft Ventricular Aneurysmectomy in Advanced Left Ventricular Dysfunction
Elefteriades J, Solomon L, Mickleborough L, Cooley D. Left Ventricular Aneurysmectomy in Advanced Left Ventricular Dysfunction. Cardiology Clinics 1995, 13: 59-72. PMID: 7796433, DOI: 10.1016/s0733-8651(18)30062-6.Peer-Reviewed Original Research
1992
Is Cardiopulmonary Bypass Effective for Treatment of Hypothermic Arrest due to Drowning or Exposure?
Letsou G, Kopf G, Elefteriades J, Carter J, Baldwin J, Hammond G. Is Cardiopulmonary Bypass Effective for Treatment of Hypothermic Arrest due to Drowning or Exposure? JAMA Surgery 1992, 127: 525-528. PMID: 1575622, DOI: 10.1001/archsurg.1992.01420050045005.Peer-Reviewed Original ResearchConceptsCardiopulmonary bypassHypothermic arrestMedian sternotomyEmergency hospital admissionsNormal neurologic functionFull cardiopulmonary arrestFreshwater drowningHospital admissionNeurologic functionSinus bradycardiaSuch patientsThree patientsCardiopulmonary arrestFourth patientVentricular fibrillationPatientsBypassSternotomyCore temperatureResuscitationArrestExposureAsystoleBradycardiaDrowning